2. GPCR/G Protein
  3. LPL Receptor
  4. CYM5442 (Standard)

CYM5442 (Standard) is the analytical standard of CYM5442. This product is intended for research and analytical applications. CYM5442 is a potent, highly-selective and orally active sphingosine 1-phosphate (S1P1) receptor agonist with an EC50 of 1.35 nM. CYM5442 is inactive against S1P2, S1P3, S1P4, and S1P5. CYM5442 activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 exerts retinal neuroprotection. CYM5442 can easily penetrate the central nervous system (CNS).

For research use only. We do not sell to patients.

CYM5442 (Standard) Chemical Structure

CYM5442 (Standard) Chemical Structure

CAS No. : 1094042-01-9

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CYM5442 (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CYM5442 (Standard)1094042-01-9LPL ReceptorLysophospholipid ReceptorS1P1endothelin-1CNSinternalizationphosphorylationp42/p44ubiquitinationretinalganglionInhibitorinhibitorinhibit

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