1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. Phosphodiesterase-IN-3

Phosphodiesterase-IN-3 (Example 20) is a phosphodiesterase 4B inhibitor, with IC50s of <10 nM and 10-100 nM for PDE4B1 and PDE4D3, respectively. Phosphodiesterase-IN-3 has the potential for the research of idiopathic pulmonary fibrosis.

For research use only. We do not sell to patients.

Phosphodiesterase-IN-3 Chemical Structure

Phosphodiesterase-IN-3 Chemical Structure

CAS No. : 3042880-01-0

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Description

Phosphodiesterase-IN-3 (Example 20) is a phosphodiesterase 4B inhibitor, with IC50s of <10 nM and 10-100 nM for PDE4B1 and PDE4D3, respectively. Phosphodiesterase-IN-3 has the potential for the research of idiopathic pulmonary fibrosis[1].

Molecular Weight

382.39

Formula

C20H19FN4O3

CAS No.
SMILES

COC1=NC=C(C=C1)C2=C3C(N([C@H](CN3C4=C2N=CC(F)=C4)CO)C5CC5)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Phosphodiesterase-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Phosphodiesterase-IN-3
Cat. No.:
HY-172776
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