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  4. Proteasome 20S LMP2 Antibody (YA1747)

Proteasome 20S LMP2 Antibody (YA1747)

Cat. No.: HY-P82002
COA User Guide for Antibodies Technical Support

Proteasome 20S LMP2 Antibody (YA1747) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1747), targeting Proteasome beta 9, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). Proteasome 20S LMP2 Antibody (YA1747) can be used for WB, ICC/IF experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

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10 μL In-stock
50 μL In-stock
100 μL In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Proteasome 20S LMP2 Antibody (YA1747) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1747), targeting Proteasome beta 9, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). Proteasome 20S LMP2 Antibody (YA1747) can be used for WB, ICC/IF experiment in human, mouse, rat background.

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The related gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The related gene is located in the class II region of the MHC (major histocompatibility complex). Expression of The related gene is induced by gamma interferon and The related gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to related generate a mature subunit.

Gene ID
SwissProt ID
Synonyms
Beta1i; LMP2; PSMB 9; PSMB6i; PSMB9; RING12
Molecular Weight

Predicted band size: 23 kDa; Observed band size: 23 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Cell Biology

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

Dilution Ratio

WB: 1/500-1/1000;IF: 1/50-1/200

Application

WB, ICC/IF

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthetic peptide of human Proteasome 20S LMP2

Database
Documentation

Proteasome 20S LMP2 Antibody (YA1747) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Proteasome 20S LMP2 Antibody (YA1747)
Cat. No.:
HY-P82002
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