2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. (S,R,S)-AHPC-CO-C2-phenylboronic acid

(S,R,S)-AHPC-CO-C2-phenylboronic acid is an E3 ligase ligand-linker conjugate that incorporates the VH032-based VHL ligand (HY-125845) and linker. (S,R,S)-AHPC-CO-C2-phenylboronic acid can be used for synthesis of PROTAC AF151 (HY-174873).

For research use only. We do not sell to patients.

(S,R,S)-AHPC-CO-C2-phenylboronic acid

(S,R,S)-AHPC-CO-C2-phenylboronic acid Chemical Structure

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(S,R,S)-AHPC-CO-C2-phenylboronic acid Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Description

(S,R,S)-AHPC-CO-C2-phenylboronic acid is an E3 ligase ligand-linker conjugate that incorporates the VH032-based VHL ligand (HY-125845) and linker. (S,R,S)-AHPC-CO-C2-phenylboronic acid can be used for synthesis of PROTAC AF151 (HY-174873)[1].

IC50 & Target[1]

VHL

 

Molecular Weight

606.54

Formula

C31H39BN4O6S
SMILES

CC1=C(C2=CC=C(CNC([C@H]3N(C([C@@H](NC(CCC4=CC=C(B(O)O)C=C4)=O)C(C)(C)C)=O)C[C@H](O)C3)=O)C=C2)SC=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(S,R,S)-AHPC-CO-C2-phenylboronic acid Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S,R,S)-AHPC-CO-C2-phenylboronic acidE3 Ligase Ligand-Linker ConjugatesVH032VHLPROTACInhibitorinhibitorinhibit

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(S,R,S)-AHPC-CO-C2-phenylboronic acid
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