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  3. BTD probe-1

BTD probe-1 is a benzothiazine-based chemoselective probe for selective labeling of protein S-sulfenic acids in vitro. BTD probe-1 selectively modify sulfenic acid residues in proteins.

For research use only. We do not sell to patients.

BTD probe-1

BTD probe-1 Chemical Structure

CAS No. : 2095485-22-4

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Description

BTD probe-1 is a benzothiazine-based chemoselective probe for selective labeling of protein S-sulfenic acids in vitro. BTD probe-1 selectively modify sulfenic acid residues in proteins[1].

Molecular Weight

263.31

Formula

C13H13NO3S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1CS(N(CCCC#C)C2=CC=CC=C12)(=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (379.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7978 mL 18.9890 mL 37.9781 mL
5 mM 0.7596 mL 3.7978 mL 7.5956 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7978 mL 18.9890 mL 37.9780 mL 94.9451 mL
5 mM 0.7596 mL 3.7978 mL 7.5956 mL 18.9890 mL
10 mM 0.3798 mL 1.8989 mL 3.7978 mL 9.4945 mL
15 mM 0.2532 mL 1.2659 mL 2.5319 mL 6.3297 mL
20 mM 0.1899 mL 0.9495 mL 1.8989 mL 4.7473 mL
25 mM 0.1519 mL 0.7596 mL 1.5191 mL 3.7978 mL
30 mM 0.1266 mL 0.6330 mL 1.2659 mL 3.1648 mL
40 mM 0.0949 mL 0.4747 mL 0.9495 mL 2.3736 mL
50 mM 0.0760 mL 0.3798 mL 0.7596 mL 1.8989 mL
60 mM 0.0633 mL 0.3165 mL 0.6330 mL 1.5824 mL
80 mM 0.0475 mL 0.2374 mL 0.4747 mL 1.1868 mL
100 mM 0.0380 mL 0.1899 mL 0.3798 mL 0.9495 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BTD probe-1
Cat. No.:
HY-D2186
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