2. Anti-infection
  3. SARS-CoV
  4. Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34)

Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) 

Cat. No.: HY-P990814
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Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to SARS-CoV-2 S protein. Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) reacts with the receptor binding domain (RBD) epitope B in the spike (S) protein of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2). Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) can block the binding of the SARS-CoV-2 S protein to angiotensin-converting enzyme 2 (ACE2). Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) can be used for the research of SARS-CoV-2 infection.

For research use only. We do not sell to patients.

Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34)

Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) Chemical Structure

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Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) Related Antibodies

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Description

Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to SARS-CoV-2 S protein. Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) reacts with the receptor binding domain (RBD) epitope B in the spike (S) protein of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2). Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) can block the binding of the SARS-CoV-2 S protein to angiotensin-converting enzyme 2 (ACE2). Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) can be used for the research of SARS-CoV-2 infection[1].

Isotype

Mouse IgG1 kappa
Species Reactivity

Virus
IC50 & Target

SARS-CoV-2 S protein
In Vivo

Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) (100 μg, i.p., 24 h prior to infection) protects against virus challenge in SARS-CoV-2 WA1/2020 virus infected K18-hACE2 transgenic mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: SARS-CoV-2 WA1/2020 virus infected K18-hACE2 transgenic mice models[1]
Dosage: 100 μg
Administration: Intraperitoneally injection, 24 h prior to infection
Result: Maintained body weight until 6-7 days, at which point we observed a 10% weight loss.
Gene ID
Accession
Application

ELISA, FACS, Functional assay, Research in vivo
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

150 kDa

SMILES

[Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34)]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34)SARS-CoVSARS coronavirusSARS-CoV-2RBDACE2WA1/2020Inhibitorinhibitorinhibit

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