2. Anti-infection Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Bacterial Reactive Oxygen Species (ROS)
  4. Epanorin

Epanorin is a secondary metabolite of the Acarospora lichenic species Epanorin can inhibit cancer cells proliferation, ROS production and induce G0/G1 phase arrest. Epanorin shows antibacterial activity. Epanorin can be used for the researches of cancer and infection, such as breast cancer and S. pneumonia infection.

For research use only. We do not sell to patients.

Epanorin

Epanorin Chemical Structure

CAS No. : 18463-10-0

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Epanorin Related Antibodies

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Description

Epanorin is a secondary metabolite of the Acarospora lichenic species Epanorin can inhibit cancer cells proliferation, ROS production and induce G0/G1 phase arrest. Epanorin shows antibacterial activity. Epanorin can be used for the researches of cancer and infection, such as breast cancer and S. pneumonia infection[1][2].

In Vitro

Epanorin shows potent inhibitory activity against breast cancer cell line (up to 80%) and moderate inhibitory activity for meningioma (up to 40%)[1].
Epanorin (28 μM) reduces cell colonies in MCF-7 cells[1].
Epanorin (28 μM, 48 h) reduces ROS production in Doxorubicin (HY-15142A)-induced MCF-7 cells[1].
Epanorin (28 μM, 48 h) induces G0/G1 phase arrest in MCF-7 cells[1].
Epanorin (28 μM, 12 h) does not induce detectable DNA fragmentation in MCF-7 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Epanorin Related Antibodies

Cell Cycle Analysis[1]

Cell Line: MCF-7 cells
Concentration: 28 μM
Incubation Time: 48 h
Result: Increased the cells on G0 phase.
Reduced cells on S phase.
Molecular Weight

435.47

Formula

C25H25NO6
CAS No.
SMILES

COC([C@H](CC(C)C)NC(/C(C1=CC=CC=C1)=C2C(O)=C(C3=CC=CC=C3)C(O/2)=O)=O)=O
Structure Classification
Initial Source

Acarospora schleicheri
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Epanorin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Epanorin18463-10-0BacterialReactive Oxygen Species (ROS)CancerCytotoxicityMutagenesisCell cycleS. pneumoniaInhibitorinhibitorinhibit

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