2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. (S)-AZD0022

(S)-AZD0022 is an isomer of AZD0022, AZD0022 is a selective and orally active KRASG12D inhibitor. AZD0022 inhibits KRAS pathway suppression in the GP2D xenograft model.

For research use only. We do not sell to patients.

(S)-AZD0022

(S)-AZD0022 Chemical Structure

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Other Forms of (S)-AZD0022:

(S)-AZD0022 Related Antibodies

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Description

(S)-AZD0022 is an isomer of AZD0022, AZD0022 is a selective and orally active KRASG12D inhibitor. AZD0022 inhibits KRAS pathway suppression in the GP2D xenograft model[1].

Molecular Weight

614.64

Formula

C34H30F4N6O
Appearance

Solid

SMILES

FC1=C(C#C)C2=[C@@]([C@@]3=C(F)C(N=C(OC[C@]4(C[C@@H](F)C5)N5CCC4)N=C6N7C[C@H]8N[C@H](C=C8)C7)=C6C=C3F)C=C(N)C=C2C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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(S)-AZD0022 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-AZD0022RasKRAS G12DInhibitorisomerinhibitorinhibit

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