Peldesine dihydrochloride (Standard)

Cat. No.: HY-106934AR Purity: ≥98%: Handling Instructions
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Peldesine (dihydrochloride) (Standard) is the analytical standard of Peldesine (dihydrochloride). This product is intended for research and analytical applications. Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine dihydrochloride is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine dihydrochloride has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research.

For research use only. We do not sell to patients.

Peldesine dihydrochloride (Standard) Chemical Structure

CAS No. : 2772702-10-8

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Description	Peldesine (dihydrochloride) (Standard) is the analytical standard of Peldesine (dihydrochloride). This product is intended for research and analytical applications. Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine dihydrochloride is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine dihydrochloride has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research.
Molecular Weight	314.17
Formula	C₁₂H₁₃Cl₂N₅O
CAS No.	2772702-10-8
SMILES	Cl[H].O=C1C(NC=C2CC3=CC=CN=C3)=C2N=C(N)N1.Cl[H]
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Peldesine dihydrochloride (Standard) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Peldesine dihydrochloride (Standard)2772702-10-8Nucleoside Antimetabolite/AnalogHIVHuman immunodeficiency virusnucleosidephosphorylaseT-cellPNPimmunosuppressivedGuoIL-2inosinepsoriasislymphomaInhibitorinhibitorinhibit

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Peldesine dihydrochloride (Standard)

Product Information

Purity & Documentation

Customer Review

Peldesine dihydrochloride (Standard) Related Classifications

Molarity Calculator

Dilution Calculator