2. GPCR/G Protein Cell Cycle/DNA Damage
  3. P2Y Receptor DNA/RNA Synthesis
  4. Uridine 5'-O-thiodiphosphate trisodium

Uridine 5'-O-thiodiphosphate trisodium  (Synonyms: UDP-β-S trisodium)

Cat. No.: HY-137608A
Handling Instructions Technical Support

Uridine 5'-O-thiodiphosphate (trisodium) (UDP-β-S (trisodium)) is a purinergic P2Y6 receptor agonist. Uridine 5'-O-thiodiphosphate (trisodium) selectively induces accumulation of inositol phosphates in 1321N1 cells expressing P2Y6 receptors (EC50 = 28 nM). Uridine 5'-O-thiodiphosphate (trisodium) induces DNA synthesis in rat aortic smooth muscle cells.

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Uridine 5'-O-thiodiphosphate trisodium

Uridine 5'-O-thiodiphosphate trisodium Chemical Structure

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Other Forms of Uridine 5'-O-thiodiphosphate trisodium:

Uridine 5'-O-thiodiphosphate trisodium Related Antibodies

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Description

Uridine 5'-O-thiodiphosphate (trisodium) (UDP-β-S (trisodium)) is a purinergic P2Y6 receptor agonist. Uridine 5'-O-thiodiphosphate (trisodium) selectively induces accumulation of inositol phosphates in 1321N1 cells expressing P2Y6 receptors (EC50 = 28 nM). Uridine 5'-O-thiodiphosphate (trisodium) induces DNA synthesis in rat aortic smooth muscle cells[1].

IC50 & Target[1]

P2Y6 Receptor

28 nM (EC50)

Molecular Weight

486.17

Formula

C9H11N2Na3O11P2S
SMILES

O[C@H]1[C@@H](O)[C@H](N2C=CC(NC2=O)=O)O[C@@H]1COP(OP(O[Na])(S[Na])=O)(O[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Uridine 5'-O-thiodiphosphate trisodium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Uridine 5'-O-thiodiphosphate trisodiumUDP-β-S trisodiumP2Y ReceptorDNA/RNA Synthesisaortic smooth muscle cells1321N1 cellsinositol phosphatesInhibitorinhibitorinhibit

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