2. Immunology/Inflammation
  3. NO Synthase
  4. Guanidino ethyl disulfide

Guanidino ethyl disulfide (GED) (Compound 23) is a NO Synthase (NOS) inhibitor with EC50s of 110, 630 and 180  μM for iNOS, eNOS and bNOS, respectivly. Guanidino ethyl disulfide effectively inhibits nitrite production in J774.2 macrophages. Guanidino ethyl disulfide can be used for circulatory shock, inflammation and neurological diseases research.

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Guanidino ethyl disulfide

Guanidino ethyl disulfide Chemical Structure

CAS No. : 1072-13-5

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Guanidino ethyl disulfide Related Antibodies

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Description

Guanidino ethyl disulfide (GED) (Compound 23) is a NO Synthase (NOS) inhibitor with EC50s of 110, 630 and 180  μM for iNOS, eNOS and bNOS, respectivly. Guanidino ethyl disulfide effectively inhibits nitrite production in J774.2 macrophages. Guanidino ethyl disulfide can be used for circulatory shock, inflammation and neurological diseases research[1].

IC50 & Target[1]

iNOS

110 μM (EC50)

eNOS

630 μM (EC50)

bNOS

180 μM (EC50)

Molecular Weight

236.36

Formula

C6H16N6S2
CAS No.
SMILES

N=C(NCCSSCCNC(N)=N)N
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Guanidino ethyl disulfide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Guanidino ethyl disulfide1072-13-5NO SynthaseNitric oxide synthasesNOSInhibitoriNOSeNOSbNOSJ774.2 macrophageCirculatory shockInflammationNeurological diseasesinhibitorinhibit

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