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D-SNAP  (Synonyms: S-Nitroso-N-acetylpenicillamine)

Cat. No.: HY-101013
SDS
Handling Instructions Technical Support

D-SNAP (S-Nitroso-N-acetylpenicillamine) can Generate nitric oxide and form superoxides spontaneously under physiological conditions and is often used to probe the cell stress response and stimulate calcium-independent synaptic vesicle release.

For research use only. We do not sell to patients.

D-SNAP

D-SNAP Chemical Structure

CAS No. : 79032-48-7

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Based on 1 publication(s) in Google Scholar

D-SNAP Related Antibodies

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Description

D-SNAP (S-Nitroso-N-acetylpenicillamine) can Generate nitric oxide and form superoxides spontaneously under physiological conditions and is often used to probe the cell stress response and stimulate calcium-independent synaptic vesicle release.

Cellular Effect
Cell Line Type Value Description References
HT-29 EC50
> 1000 μM
Compound: SNAP
Apoptosis induction in human HT29 cells after 24 hrs
Apoptosis induction in human HT29 cells after 24 hrs
[PMID: 17441704]
Molecular Weight

220.25

Formula

C7H12N2O4S
CAS No.
Appearance

Solid

Color

Light green to green

SMILES

O=NSC(C)(C)[C@H](C(O)=O)NC(C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (454.03 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5403 mL 22.7015 mL 45.4030 mL
5 mM 0.9081 mL 4.5403 mL 9.0806 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.5403 mL 22.7015 mL 45.4030 mL 113.5074 mL
5 mM 0.9081 mL 4.5403 mL 9.0806 mL 22.7015 mL
10 mM 0.4540 mL 2.2701 mL 4.5403 mL 11.3507 mL
15 mM 0.3027 mL 1.5134 mL 3.0269 mL 7.5672 mL
20 mM 0.2270 mL 1.1351 mL 2.2701 mL 5.6754 mL
25 mM 0.1816 mL 0.9081 mL 1.8161 mL 4.5403 mL
30 mM 0.1513 mL 0.7567 mL 1.5134 mL 3.7836 mL
40 mM 0.1135 mL 0.5675 mL 1.1351 mL 2.8377 mL
50 mM 0.0908 mL 0.4540 mL 0.9081 mL 2.2701 mL
60 mM 0.0757 mL 0.3784 mL 0.7567 mL 1.8918 mL
80 mM 0.0568 mL 0.2838 mL 0.5675 mL 1.4188 mL
100 mM 0.0454 mL 0.2270 mL 0.4540 mL 1.1351 mL
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D-SNAP Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-SNAP79032-48-7S-Nitroso-N-acetylpenicillamineFluorescent DyeInhibitorinhibitorinhibit

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