2. Metabolic Enzyme/Protease Anti-infection
  3. Succinate Dehydrogenase Fungal
  4. Succinate dehydrogenase-IN-6

Succinate dehydrogenase-IN-6 (Compound E23) is the inhibitor for succinate dehydrogenase that inhibits SDH in Rhizoctonia solani with an IC50 of 11.76 μM. Succinate dehydrogenase-IN-6 disrupts fungal cell membrane, exhibits board-spectrum antifungal activity that inhibits R. solani, V. dahliae, A. solani and C. gloeosporioides with EC50s of 0.41, 0.27, 1.15, 0.27 μg/mL, respectively. Succinate dehydrogenase-IN-6 exhibits no significant toxicity in rice and zebrafish (LC50 > 12.5 μg/mL).

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Succinate dehydrogenase-IN-6 Chemical Structure

Succinate dehydrogenase-IN-6 Chemical Structure

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Succinate dehydrogenase-IN-6 Related Antibodies

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Description

Succinate dehydrogenase-IN-6 (Compound E23) is the inhibitor for succinate dehydrogenase that inhibits SDH in Rhizoctonia solani with an IC50 of 11.76 μM. Succinate dehydrogenase-IN-6 disrupts fungal cell membrane, exhibits board-spectrum antifungal activity that inhibits R. solani, V. dahliae, A. solani and C. gloeosporioides with EC50s of 0.41, 0.27, 1.15, 0.27 μg/mL, respectively. Succinate dehydrogenase-IN-6 exhibits no significant toxicity in rice and zebrafish (LC50 > 12.5 μg/mL)[1].

Molecular Weight

316.26

Formula

C15H10F2N4O2
SMILES

O=C(C(N1)=NC2=C(C=CC=C2)C1=O)NNC3=CC=C(F)C(F)=C3
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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Succinate dehydrogenase-IN-6 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Succinate dehydrogenase-IN-6Succinate DehydrogenaseFungalrice sheath blightRhizoctonia solanizebrafishInhibitorinhibitorinhibit

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