2. Others Metabolic Enzyme/Protease NF-κB Neuronal Signaling Membrane Transporter/Ion Channel
  3. Reference Standards Glutathione S-transferase NF-κB Calcium Channel
  4. Ethacrynic acid (Standard)

Ethacrynic acid (Standard)  (Synonyms: Etacrynic acid (Standard))

Cat. No.: HY-B1640R Purity: 98.78%
COA
SDS
Handling Instructions Technical Support

Ethacrynic acid (Standard) is the analytical standard of Ethacrynic acid. This product is intended for research and analytical applications. Ethacrynic acid (Etacrynic acid) is a diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice.

For research use only. We do not sell to patients.

Ethacrynic acid (Standard)

Ethacrynic acid (Standard) Chemical Structure

CAS No. : 58-54-8

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Based on 1 publication(s) in Google Scholar

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Information
Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

303.14

Formula

C₁₃H₁₂Cl₂O₄
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)COC1=CC=C(C(C(CC)=C)=O)C(Cl)=C1Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 98.78%

SDS (392 KB)

COA (147 KB) HNMR (274 KB) RP-HPLC (420 KB) MS (232 KB)

Handling Instructions (2659 KB)
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Ethacrynic acid (Standard) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ethacrynic acid (Standard)58-54-8Etacrynic acid (Standard)Reference StandardsGlutathione S-transferaseNF-κBCalcium ChannelGlutathione transferasesGSTsNuclear factor-κBNuclear factor-kappaBCa2+ channelsCa channelsInhibitorinhibitorinhibit

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