1. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  2. HSP
  3. Antiproliferative agent-72

Antiproliferative agent-72 (Compound 10) is a Hsp90 inhibitor with a Kd of 11 nM. Antiproliferative agent-72 has antiproliferative activity with IC50s of 1.5  μM and 1.1 μM for HCT116 and NCI-N87 cells, respectively. Antiproliferative agent-72 can be used for cancers research.

For research use only. We do not sell to patients.

Antiproliferative agent-72

Antiproliferative agent-72 Chemical Structure

CAS No. : 1052646-54-4

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Description

Antiproliferative agent-72 (Compound 10) is a Hsp90 inhibitor with a Kd of 11 nM. Antiproliferative agent-72 has antiproliferative activity with IC50s of 1.5  μM and 1.1 μM for HCT116 and NCI-N87 cells, respectively. Antiproliferative agent-72 can be used for cancers research[1].

IC50 & Target[1]

HSP90

11 nM (Kd)

Molecular Weight

434.34

Formula

C20H17Cl2N3O2S

CAS No.
SMILES

ClC1=CC(Cl)=C2C=C1OCCCCOC3=CC=CC(SC4=NC(N)=NC2=C4)=C3

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antiproliferative agent-72
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HY-176538
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