1. Metabolic Enzyme/Protease Anti-infection
  2. Succinate Dehydrogenase Fungal
  3. Antifungal agent 135

Antifungal agent 135 (Compound C2), an antifungal agent, is a Succinate dehydrogenase (SDH) inhibitor with an IC50 of 1.99 μM. Antifungal agent 135 has potent antifungal activities against Valsa mali, Sclerotinia sclerotiorum and Phytophthora capsici with EC50s of 0.280, 1.11 and 0.130 mg/L, respectively. Antifungal agent 135 shows protective and curative activities against P. capsici and V. mali by effectively disrupting hyphal structural integrity and inhibiting mycelial growth.

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Antifungal agent 135

Antifungal agent 135 Chemical Structure

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Description

Antifungal agent 135 (Compound C2), an antifungal agent, is a Succinate dehydrogenase (SDH) inhibitor with an IC50 of 1.99 μM. Antifungal agent 135 has potent antifungal activities against Valsa mali, Sclerotinia sclerotiorum and Phytophthora capsici with EC50s of 0.280, 1.11 and 0.130 mg/L, respectively. Antifungal agent 135 shows protective and curative activities against P. capsici and V. mali by effectively disrupting hyphal structural integrity and inhibiting mycelial growth[1].

Molecular Weight

595.36

Formula

C21H9F12N3O2S

SMILES

O=C(NN(C(C1=CC=CC(C(F)(F)F)=C1)=O)C2=NC(C(F)(F)F)=CS2)C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antifungal agent 135
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HY-178051
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