2. Protein Tyrosine Kinase/RTK Autophagy MAPK/ERK Pathway
  3. VEGFR Autophagy PDGFR Raf RET
  4. Regorafenib Hydrochloride (Standard)

Regorafenib Hydrochloride (Standard) 

Cat. No.: HY-13308R Purity: ≥98%
Handling Instructions Technical Support

Regorafenib (Hydrochloride) (Standard) is the analytical standard of Regorafenib (Hydrochloride). This product is intended for research and analytical applications. Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

For research use only. We do not sell to patients.

Regorafenib Hydrochloride (Standard) Chemical Structure

Regorafenib Hydrochloride (Standard) Chemical Structure

CAS No. : 835621-07-3

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Description

Regorafenib (Hydrochloride) (Standard) is the analytical standard of Regorafenib (Hydrochloride). This product is intended for research and analytical applications. Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

Molecular Weight

519.28

Formula

C21H16Cl2F4N4O3
CAS No.
SMILES

ClC1=C(C(F)(F)F)C=C(NC(NC2=C(F)C=C(OC3=CC=NC(C(NC)=O)=C3)C=C2)=O)C=C1.Cl
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Regorafenib Hydrochloride (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Regorafenib Hydrochloride (Standard)835621-07-3VEGFRAutophagyPDGFRRafRETVascular endothelial growth factor receptorPlatelet-derived growth factor receptorRaf kinasesInhibitorinhibitorinhibit

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