(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol

Name: (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol
Brand: MedChemExpress
SKU: HY-W048245
Rating: 4.5 (1 reviews)

Cat. No.: HY-W048245 Purity: 98.74%: Data Sheet
SDS

COA
Handling Instructions
FAQs
Technical Support

(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol Chemical Structure

CAS No. : 190315-43-6

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

150.20

Formula

C₅H₁₀O₃S

CAS No.

190315-43-6

Appearance

Oil

Color

Light brown to brown

SMILES

O[C@H]1CS[C@H](CO)[C@H]1O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 62.5 mg/mL (416.11 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.6578 mL	33.2889 mL	66.5779 mL
5 mM	1.3316 mL	6.6578 mL	13.3156 mL
10 mM	0.6658 mL	3.3289 mL	6.6578 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.74%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (252 KB) HNMR (253 KB) RP-HPLC (250 KB)

Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.6578 mL	33.2889 mL	66.5779 mL	166.4447 mL
	5 mM	1.3316 mL	6.6578 mL	13.3156 mL	33.2889 mL
	10 mM	0.6658 mL	3.3289 mL	6.6578 mL	16.6445 mL
	15 mM	0.4439 mL	2.2193 mL	4.4385 mL	11.0963 mL
	20 mM	0.3329 mL	1.6644 mL	3.3289 mL	8.3222 mL
	25 mM	0.2663 mL	1.3316 mL	2.6631 mL	6.6578 mL
	30 mM	0.2219 mL	1.1096 mL	2.2193 mL	5.5482 mL
	40 mM	0.1664 mL	0.8322 mL	1.6644 mL	4.1611 mL
	50 mM	0.1332 mL	0.6658 mL	1.3316 mL	3.3289 mL
	60 mM	0.1110 mL	0.5548 mL	1.1096 mL	2.7741 mL
	80 mM	0.0832 mL	0.4161 mL	0.8322 mL	2.0806 mL
	100 mM	0.0666 mL	0.3329 mL	0.6658 mL	1.6644 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.