2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. ADD-17014

ADD-17014 is a L-Glu antagonist. ADD-17014 impairs presynaptic excitatory amino acid L-Glu neurotransmission. ADD-17014 is a prodrug of its β-amino alcohol metabolite, and the metabolite acts as a NMDA receptor antagonist by binding to the MK-801 site located inside the NMDA receptor or ion channel. ADD-17014 has an anticonvulsant and anti-ischemic activity. ADD-17014 can be used for neurodegenerative diseases like Parkinson’s disease, Alzheimer’s disease and stroke research.

For research use only. We do not sell to patients.

ADD-17014

ADD-17014 Chemical Structure

CAS No. : 55643-87-3

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ADD-17014 Related Antibodies

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Description

ADD-17014 is a L-Glu antagonist. ADD-17014 impairs presynaptic excitatory amino acid L-Glu neurotransmission. ADD-17014 is a prodrug of its β-amino alcohol metabolite, and the metabolite acts as a NMDA receptor antagonist by binding to the MK-801 site located inside the NMDA receptor or ion channel. ADD-17014 has an anticonvulsant and anti-ischemic activity. ADD-17014 can be used for neurodegenerative diseases like Parkinson’s disease, Alzheimer’s disease and stroke research[1][2].

Molecular Weight

258.71

Formula

C13H11ClN4
CAS No.
SMILES

ClC1=CC=C(N2N=NCC2C3=CC=NC=C3)C=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ADD-17014 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ADD-1701455643-87-3ADD17014ADD 17014mGluRMetabotropic glutamate receptorsL-GluAntagonistProdrugAnticonvulsantAnti-ischemicParkinson’s diseaseAlzheimer’s diseaseStrokeInhibitorinhibitorinhibit

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