2. Protein Tyrosine Kinase/RTK Apoptosis
  3. FLT3 c-Kit PDGFR Apoptosis
  4. Tandutinib hydrochloride (Standard)

Tandutinib hydrochloride (Standard)  (Synonyms: MLN518 hydrochloride (Standard); CT53518 hydrochloride (Standard))

Cat. No.: HY-10202AR Purity: ≥98%
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Tandutinib (hydrochloride) (Standard) is the analytical standard of Tandutinib (hydrochloride). This product is intended for research and analytical applications. Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. Tandutinib hydrochloride can be used for acute myelogenous leukemia (AML). Tandutinib hydrochloride has the ability to cross the blood-brain barrier.

For research use only. We do not sell to patients.

Tandutinib hydrochloride (Standard) Chemical Structure

Tandutinib hydrochloride (Standard) Chemical Structure

CAS No. : 2438900-70-8

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Description

Tandutinib (hydrochloride) (Standard) is the analytical standard of Tandutinib (hydrochloride). This product is intended for research and analytical applications. Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. Tandutinib hydrochloride can be used for acute myelogenous leukemia (AML). Tandutinib hydrochloride has the ability to cross the blood-brain barrier.

Molecular Weight

599.16

Formula

C31H43ClN6O4
CAS No.
SMILES

O=C(N1CCN(C2=C(C(C=C3OCCCN4CCCCC4)=NC=N2)C=C3OC)CC1)NC5=CC=C(OC(C)C)C=C5.Cl
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Tandutinib hydrochloride (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tandutinib hydrochloride (Standard)2438900-70-8MLN518 hydrochloride (Standard)CT53518 hydrochloride (Standard)FLT3c-KitPDGFRApoptosisCluster of differentiation antigen 135CD135Fms like tyrosine kinase 3SCFRCD117Platelet-derived growth factor receptorAcutemyelogenousleukemiaautophosphorylationMAPPI3FLT3-ITDblood-brainbarrierInhibitorinhibitorinhibit

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