(4S)-GLP-1 receptor agonist 14

Cat. No.: HY-164774 Purity: 99.62%: Data Sheet
COA

SDS
Handling Instructions
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(4S)-GLP-1 receptor agonist 14 (Compound 73) is a GLP-1 receptor modulator.

For research use only. We do not sell to patients.

(4S)-GLP-1 receptor agonist 14 Chemical Structure

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Other Forms of (4S)-GLP-1 receptor agonist 14:

GLP-1 receptor agonist 14 In-stock

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Biological Activity
Purity & Documentation
References
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Description

(4S)-GLP-1 receptor agonist 14 (Compound 73) is a GLP-1 receptor modulator^[1].

Molecular Weight

880.94

Formula

C₄₈H₄₆F₂N₁₀O₅

CAS No.

2758659-09-3

Appearance

Solid

Color

Light yellow to light brown

SMILES

O=C(N1[C@H](C2=C(N3C(N(C4=CC=C(N(N=C5)C)C5=C4F)C=C3)=O)N(C6=CC(C7CC7)=C(C=C6)F)N=C2CC1)C)C8=C(N9C(C=C(C%10CC(C)(OCC%10)C)C=C9)=C8)C%11(C%12=NOC(N%12)=O)CC%11

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (141.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1352 mL	5.6758 mL	11.3515 mL
5 mM	0.2270 mL	1.1352 mL	2.2703 mL
10 mM	0.1135 mL	0.5676 mL	1.1352 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.62%

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Data Sheet (274 KB) SDS (251 KB)

COA (260 KB) HNMR (353 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. REN Z, et, al. Tetrahydropyrazolo-pyrazinyl-dihydroimidazolone or tetrahydropyrazolo-pyridinyl-dihydroimidazolone compounds and methods of using same. WO2022017338A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1352 mL	5.6758 mL	11.3515 mL	28.3788 mL
	5 mM	0.2270 mL	1.1352 mL	2.2703 mL	5.6758 mL
	10 mM	0.1135 mL	0.5676 mL	1.1352 mL	2.8379 mL
	15 mM	0.0757 mL	0.3784 mL	0.7568 mL	1.8919 mL
	20 mM	0.0568 mL	0.2838 mL	0.5676 mL	1.4189 mL
	25 mM	0.0454 mL	0.2270 mL	0.4541 mL	1.1352 mL
	30 mM	0.0378 mL	0.1892 mL	0.3784 mL	0.9460 mL
	40 mM	0.0284 mL	0.1419 mL	0.2838 mL	0.7095 mL
	50 mM	0.0227 mL	0.1135 mL	0.2270 mL	0.5676 mL
	60 mM	0.0189 mL	0.0946 mL	0.1892 mL	0.4730 mL
	80 mM	0.0142 mL	0.0709 mL	0.1419 mL	0.3547 mL
	100 mM	0.0114 mL	0.0568 mL	0.1135 mL	0.2838 mL