2. Others Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Membrane Transporter/Ion Channel Neuronal Signaling Autophagy Apoptosis
  3. Reference Standards PPAR TRP Channel Autophagy Ferroptosis
  4. Rosiglitazone maleate (Standard)

Rosiglitazone maleate (Standard)  (Synonyms: BRL 49653C (Standard))

Cat. No.: HY-14600R
Handling Instructions Technical Support

Rosiglitazone (maleate) (Standard) is the analytical standard of Rosiglitazone (maleate). This product is intended for research and analytical applications. Rosiglitazone maleate (BRL 49653C) is a potent and selective activator of PPARγ, with EC50s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively, and a Kd of appr 40 nM for PPARγ; Rosiglitazone maleate is also an modulator of TRP channels, inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5).

For research use only. We do not sell to patients.

Rosiglitazone maleate (Standard)

Rosiglitazone maleate (Standard) Chemical Structure

CAS No. : 155141-29-0

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100 mg Get quote 5 - 7 weeks 4 - 6 weeks 4 - 6 weeks
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Information

Rosiglitazone (maleate) (Standard) is the analytical standard of Rosiglitazone (maleate). This product is intended for research and analytical applications. Rosiglitazone maleate (BRL 49653C) is a potent and selective activator of PPARγ, with EC50s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively, and a Kd of appr 40 nM for PPARγ; Rosiglitazone maleate is also an modulator of TRP channels, inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5).

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

473.50

Formula

C22H23N3O7S
CAS No.
SMILES

O=C(O)/C=C\C(O)=O.CN(CCOC1=CC=C(CC2C(NC(S2)=O)=O)C=C1)C3=CC=CC=N3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Rosiglitazone maleate (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rosiglitazone maleate (Standard)155141-29-0BRL 49653C (Standard)Reference StandardsPPARTRP ChannelAutophagyFerroptosisPeroxisome proliferator-activated receptorsTransient receptor potential channelsInhibitorinhibitorinhibit

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