2. PROTAC Epigenetics
  3. PROTACs Epigenetic Reader Domain
  4. PROTAC SMARCA2/4 degrader-39

PROTAC SMARCA2/4 degrader-39 (Compound 7) is a selective degrader of SMARCA2 (BRM) and SMARCA4 (BRG1) PROTAC. PROTAC SMARCA2/4 degrader-39 is promising for research of oncology, such as non-small cell lung cancer and colorectal cancer. (Pink: BRM/BRG1 ligand 5 (HY-178886); Black: Linker Piperazine (HY-B0912); Blue: (S)-Deoxy-thalidomide (HY-168055))

For research use only. We do not sell to patients.

PROTAC SMARCA2/4 degrader-39

PROTAC SMARCA2/4 degrader-39 Chemical Structure

CAS No. : 3099581-74-2

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PROTAC SMARCA2/4 degrader-39 Related Antibodies

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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Description

PROTAC SMARCA2/4 degrader-39 (Compound 7) is a selective degrader of SMARCA2 (BRM) and SMARCA4 (BRG1) PROTAC. PROTAC SMARCA2/4 degrader-39 is promising for research of oncology, such as non-small cell lung cancer and colorectal cancer[1]. (Pink: BRM/BRG1 ligand 5 (HY-178886); Black: Linker Piperazine (HY-B0912); Blue: (S)-Deoxy-thalidomide (HY-168055))

Molecular Weight

757.84

Formula

C41H43N9O6
CAS No.
SMILES

CC[C@@](N1C2)(CNC3=C1C=C(C4=C(O)C=CC=C4)N=N3)C[C@H]2OC(N=C5)=C(C)C=C5C(N(CC6)CCN6C7=CC(C8=O)=C(C=C7)CN8[C@H](C(N9)=O)CCC9=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC SMARCA2/4 degrader-39 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC SMARCA2/4 degrader-393099581-74-2PROTACsEpigenetic Reader DomainBRG1BRMoncologycolorectal cancerInhibitorinhibitorinhibit

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