2. Anti-infection Metabolic Enzyme/Protease
  3. HIV Reverse Transcriptase HIV Integrase HIV Protease
  4. Ethyl salvianolate A

Ethyl salvianolate A  (Synonyms: Ethyl salvionolate A)

Cat. No.: HY-N16050 Purity: 91.38%
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Ethyl salvianolate A (Ethyl salvionolate A) is an anti-HIV-1 compound that can be extracted from the roots of Salvia yunnanensis. Ethyl salvianolate A inhibits P24 antigen in HIV-1 infected MT-4 cell cultures (EC50: 1.44 μg/mL). Ethyl salvianolate A inhibits HIV-1 replicative enzymes, with IC50s of 56.38 μM (Reverse transcriptase), 12.03 μM (Protease), 14.54 μM (Integrase), respectively.

For research use only. We do not sell to patients.

Ethyl salvianolate A

Ethyl salvianolate A Chemical Structure

CAS No. : 1015171-68-2

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Ethyl salvianolate A Related Antibodies

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Description

Ethyl salvianolate A (Ethyl salvionolate A) is an anti-HIV-1 compound that can be extracted from the roots of Salvia yunnanensis. Ethyl salvianolate A inhibits P24 antigen in HIV-1 infected MT-4 cell cultures (EC50: 1.44 μg/mL). Ethyl salvianolate A inhibits HIV-1 replicative enzymes, with IC50s of 56.38 μM (Reverse transcriptase), 12.03 μM (Protease), 14.54 μM (Integrase), respectively[1].

IC50 & Target[1]

HIV-1

1.44 μg/mL (EC50)

Molecular Weight

522.50

Formula

C28H26O10
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

OC(C=C1/C=C/C2=C(C=CC(O)=C2O)/C=C/C(O[C@@H](C(OCC)=O)CC3=CC(O)=C(C=C3)O)=O)=C(C=C1)O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (191.39 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9139 mL 9.5694 mL 19.1388 mL
5 mM 0.3828 mL 1.9139 mL 3.8278 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9139 mL 9.5694 mL 19.1388 mL 47.8469 mL
5 mM 0.3828 mL 1.9139 mL 3.8278 mL 9.5694 mL
10 mM 0.1914 mL 0.9569 mL 1.9139 mL 4.7847 mL
15 mM 0.1276 mL 0.6380 mL 1.2759 mL 3.1898 mL
20 mM 0.0957 mL 0.4785 mL 0.9569 mL 2.3923 mL
25 mM 0.0766 mL 0.3828 mL 0.7656 mL 1.9139 mL
30 mM 0.0638 mL 0.3190 mL 0.6380 mL 1.5949 mL
40 mM 0.0478 mL 0.2392 mL 0.4785 mL 1.1962 mL
50 mM 0.0383 mL 0.1914 mL 0.3828 mL 0.9569 mL
60 mM 0.0319 mL 0.1595 mL 0.3190 mL 0.7974 mL
80 mM 0.0239 mL 0.1196 mL 0.2392 mL 0.5981 mL
100 mM 0.0191 mL 0.0957 mL 0.1914 mL 0.4785 mL
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Ethyl salvianolate A Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ethyl salvianolate A1015171-68-2 Ethyl salvionolate AHIVReverse TranscriptaseHIV IntegraseHIV ProteaseHuman immunodeficiency virusHIV-1 infectionMT-4 cellInhibitorinhibitorinhibit

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