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  4. Proteasome 20S C2/HC2 Antibody (YA2301)

Proteasome 20S C2/HC2 Antibody (YA2301)

Cat. No.: HY-P82556
COA User Guide for Antibodies Technical Support

Proteasome 20S C2/HC2 Antibody (YA2301) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2301), targeting PSMA1, with a predicted molecular weight of 30 kDa (observed band size: 30 kDa). Proteasome 20S C2/HC2 Antibody (YA2301) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL In-stock
50 μL In-stock
100 μL In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Proteasome 20S C2/HC2 Antibody (YA2301) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2301), targeting PSMA1, with a predicted molecular weight of 30 kDa (observed band size: 30 kDa). Proteasome 20S C2/HC2 Antibody (YA2301) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

Background

PSMA1 is a component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. When associated with two 19S regulatory particles, it forms the 26S proteasome and participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in maintaining protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, as well as proteins no longer needed. When associated with PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation, which is required in pathways such as spermatogenesis (20S-PA200 complex) or the generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

Gene ID
SwissProt ID
Synonyms
NU; HC2; PROS30; psmA1; PSC2; Proteasome 20S C2
Molecular Weight

Predicted band size: 30 kDa; Observed band size: 30 kDa

Purity

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

RRID
Research Field

Cell Biology

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/50;FC: 1/50-1/100

Application

WB, IHC-P, ICC/IF, IP, FC

Appearance

Liquid

Formulation

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human Proteasome 20S C2

Database
Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Proteasome 20S C2/HC2 Antibody (YA2301)
Cat. No.:
HY-P82556
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