Activated T Subunit

Cat. No.: HY-153406 Purity: 99.64%: Data Sheet
SDS

COA
Handling Instructions
FAQs
Technical Support

Activated T Subunit can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. It can be used for research of muscular dystrophy.

For research use only. We do not sell to patients.

Activated T Subunit Chemical Structure

CAS No. : 956139-30-3

Size	Stock	Quantity
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

609.05

Formula

C₃₁H₃₄ClN₄O₅P

CAS No.

956139-30-3

Appearance

Solid

Color

White to off-white

SMILES

O=C1NC(N([C@@H]2O[C@@H](CN(C(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C2)COP(Cl)(N(C)C)=O)C=C1C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (164.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6419 mL	8.2095 mL	16.4190 mL
5 mM	0.3284 mL	1.6419 mL	3.2838 mL
10 mM	0.1642 mL	0.8210 mL	1.6419 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.64%

Select Batch:

Data Sheet (278 KB) SDS (416 KB)

COA (263 KB) HNMR (294 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Passini MA, et al. Exon skipping oligomer conjugates for muscular dystrophy. World Intellectual Property Organization, WO2018118599 A1. 2018-06-28.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6419 mL	8.2095 mL	16.4190 mL	41.0475 mL
	5 mM	0.3284 mL	1.6419 mL	3.2838 mL	8.2095 mL
	10 mM	0.1642 mL	0.8210 mL	1.6419 mL	4.1048 mL
	15 mM	0.1095 mL	0.5473 mL	1.0946 mL	2.7365 mL
	20 mM	0.0821 mL	0.4105 mL	0.8210 mL	2.0524 mL
	25 mM	0.0657 mL	0.3284 mL	0.6568 mL	1.6419 mL
	30 mM	0.0547 mL	0.2737 mL	0.5473 mL	1.3683 mL
	40 mM	0.0410 mL	0.2052 mL	0.4105 mL	1.0262 mL
	50 mM	0.0328 mL	0.1642 mL	0.3284 mL	0.8210 mL
	60 mM	0.0274 mL	0.1368 mL	0.2737 mL	0.6841 mL
	80 mM	0.0205 mL	0.1026 mL	0.2052 mL	0.5131 mL
	100 mM	0.0164 mL	0.0821 mL	0.1642 mL	0.4105 mL