2. Cell Cycle/DNA Damage Protein Tyrosine Kinase/RTK
  3. Haspin Kinase CDK DYRK
  4. Haspin-IN-1

Haspin-IN-1 (compound 2a) is a haspin inhibitor with an IC50 of 119 nM. Haspin-IN-1 also inbibits CLK1 and DYRK1A with IC50s of 221 nM and 916.3 nM, respectively.

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Haspin-IN-1 Chemical Structure

Haspin-IN-1 Chemical Structure

CAS No. : 2768474-30-0

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Haspin-IN-1 Related Antibodies

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DYRK1 DYRK2 DYRK3 DYRK4

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Description

Haspin-IN-1 (compound 2a) is a haspin inhibitor with an IC50 of 119 nM. Haspin-IN-1 also inbibits CLK1 and DYRK1A with IC50s of 221 nM and 916.3 nM, respectively[1].

IC50 & Target[1]

Haspin Kinase

119 nM (IC50)

CLK1

221 nM (IC50)

DYRK1A

916.3 nM (IC50)

Molecular Weight

272.28

Formula

C12H8N4O2S
CAS No.
SMILES

CSC1=NC2=C(C3=C(C=C2C=N1)C=NC=C3)[N+]([O-])=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Haspin-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Haspin-IN-12768474-30-0Haspin KinaseCDKDYRKCyclin dependent kinaseDual specificity tyrosine phosphorylation regulated kinaseDual specificity tyrosine regulated kinaseCLK1DYRK1AanticancerInhibitorinhibitorinhibit

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