2. GPCR/G Protein
  3. Neuropeptide S Receptor
  4. SHA 68 (Standard)

SHA 68 (Standard) is the analytical standard of SHA 68. This product is intended for research and analytical applications. SHA 68 is a potent and selective non-peptide neuropeptide S receptor (NPSR) antagonist with IC50s of 22.0 and 23.8 nM for NPSR Asn107 and NPSR Ile107, respectively. SHA 68 has limited the blood-brain barrier (BBB) penetration and the activity in neuralgia.

For research use only. We do not sell to patients.

SHA 68 (Standard) Chemical Structure

SHA 68 (Standard) Chemical Structure

CAS No. : 847553-89-3

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Description
Molecular Weight

445.49

Formula

C26H24FN3O3
CAS No.
SMILES

O=C(N1CC2N(C(OC2(C3=CC=CC=C3)C4=CC=CC=C4)=O)CC1)NCC5=CC=C(F)C=C5
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SHA 68 (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SHA 68 (Standard)847553-89-3Neuropeptide S ReceptorNPSRGPR154Vasopressin receptor-related receptor 1VRR1non-peptideneuropeptideSreceptorAsn107NPSR Ile107BBBneuralgiaInhibitorinhibitorinhibit

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