2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. EGFR d747-752/P753S Recombinant Human Active Protein Kinase

EGFR d747-752/P753S Recombinant Human Active Protein Kinase 

Cat. No.: HY-E70702
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EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR d747-752/P753S Recombinant Human Active Protein Kinase is a recombinant EGFR d747-752/P753S protein that can be used to study EGFR d747-752/P753S-related functions.

For research use only. We do not sell to patients.

EGFR d747-752/P753S Recombinant Human Active Protein Kinase

EGFR d747-752/P753S Recombinant Human Active Protein Kinase Chemical Structure

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EGFR d747-752/P753S Recombinant Human Active Protein Kinase Related Antibodies

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Description

EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR d747-752/P753S Recombinant Human Active Protein Kinase is a recombinant EGFR d747-752/P753S protein that can be used to study EGFR d747-752/P753S-related functions[1].

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[EGFR d747-752/P753S Recombinant Human Active Protein Kinase]
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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EGFR d747-752/P753S Recombinant Human Active Protein Kinase Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR d747-752/P753S Recombinant Human Active Protein KinaseEGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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EGFR d747-752/P753S Recombinant Human Active Protein Kinase
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