1. Apoptosis
  2. DAPK
  3. DAPK1-IN-1

DAPK1-IN-1 (compound 10) is a death-associated protein kinase 1 (DAPK1) inhibitor with a Kd value of 0.63 μM. DAPK1-IN-1 can be used in Alzheimer’s disease research.

For research use only. We do not sell to patients.

DAPK1-IN-1 Chemical Structure

DAPK1-IN-1 Chemical Structure

CAS No. : 1429522-04-2

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Based on 1 publication(s) in Google Scholar

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Description

DAPK1-IN-1 (compound 10) is a death-associated protein kinase 1 (DAPK1) inhibitor with a Kd value of 0.63 μM. DAPK1-IN-1 can be used in Alzheimer’s disease research[1].

Molecular Weight

335.15

Formula

C15H11BrO4

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=CC=C(C=C1O)O)/C=C/C2=CC=C(C(Br)=C2)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (298.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9837 mL 14.9187 mL 29.8374 mL
5 mM 0.5967 mL 2.9837 mL 5.9675 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9837 mL 14.9187 mL 29.8374 mL 74.5935 mL
5 mM 0.5967 mL 2.9837 mL 5.9675 mL 14.9187 mL
10 mM 0.2984 mL 1.4919 mL 2.9837 mL 7.4593 mL
15 mM 0.1989 mL 0.9946 mL 1.9892 mL 4.9729 mL
20 mM 0.1492 mL 0.7459 mL 1.4919 mL 3.7297 mL
25 mM 0.1193 mL 0.5967 mL 1.1935 mL 2.9837 mL
30 mM 0.0995 mL 0.4973 mL 0.9946 mL 2.4864 mL
40 mM 0.0746 mL 0.3730 mL 0.7459 mL 1.8648 mL
50 mM 0.0597 mL 0.2984 mL 0.5967 mL 1.4919 mL
60 mM 0.0497 mL 0.2486 mL 0.4973 mL 1.2432 mL
80 mM 0.0373 mL 0.1865 mL 0.3730 mL 0.9324 mL
100 mM 0.0298 mL 0.1492 mL 0.2984 mL 0.7459 mL
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DAPK1-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DAPK1-IN-1
Cat. No.:
HY-169109
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