2. Cell Cycle/DNA Damage
  3. G-quadruplex
  4. Pyridostatin trihydrochloride

Pyridostatin trihydrochloride  (Synonyms: RR82 trihydrochloride)

Cat. No.: HY-15176C
Handling Instructions Technical Support

Pyridostatin (RR82) trihydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin trihydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin trihydrochloride targets the proto-oncogene Src. Pyridostatin trihydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells.

For research use only. We do not sell to patients.

Pyridostatin trihydrochloride

Pyridostatin trihydrochloride Chemical Structure

CAS No. : 2517456-88-9

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Pyridostatin trihydrochloride Related Antibodies

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Description

Pyridostatin (RR82) trihydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin trihydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin trihydrochloride targets the proto-oncogene Src. Pyridostatin trihydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells[1][2].

Molecular Weight

706.02

Formula

C31H35Cl3N8O5
CAS No.
SMILES

O=C(C1=CC(OCCN)=CC(C(NC2=NC3=C(C(OCCN)=C2)C=CC=C3)=O)=N1)NC4=CC(OCCN)=C5C=CC=CC5=N4.Cl.Cl.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Pyridostatin trihydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyridostatin trihydrochloride2517456-88-9RR82 trihydrochlorideG-quadruplexstructureDNAdamageneurodegenerationDSBcyclearrestSRCInhibitorinhibitorinhibit

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