1. Immunology/Inflammation
  2. MHC
  3. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S)

Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) 

Cat. No.: HY-P990185
Technical Support

Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse/rat MHC Class II. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) reacts with mouse MHC Class II alloantigen I-Ek and the rat MHC class II alloantigen RT1D. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) blocks antigen presentation. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) can be used for the research of immunology and cancer.

For research use only. We do not sell to patients.

Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S)

Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) Chemical Structure

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Description

Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse/rat MHC Class II. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) reacts with mouse MHC Class II alloantigen I-Ek and the rat MHC class II alloantigen RT1D. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) blocks antigen presentation. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) can be used for the research of immunology and cancer[1].

Isotype

Mouse IgG2a kappa

Recommend Isotype Controls
Species Reactivity

Mouse/Rat

In Vitro

Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) (10 μg/mL, 72 h) blocks RT1-D–restricted Ag presentation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) (s.c., at day 2 and 4) blocks the activation of an I-Er-restricted T cell hybridoma in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

ELISA, FACS, Functional assay, Research in vivo

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Molecular Weight

150 kDa

SMILES

[Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S)]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S)
Cat. No.:
HY-P990185
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