PSMD11 Antibody (YA5585)

PSMD11 Antibody (YA5585) is a mouse-derived and non-conjugated IgG3 monoclonal antibody, targeting to PSMD11. It can be applicated for WB, ICC/IF, ELISA assays, in the background of human, mouse, rat.

PSMD11 is a component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in maintaining protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, as well as proteins whose functions are no longer required. Consequently, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, and DNA damage repair. Within the complex, PSMD11 is essential for proteasome assembly. It plays a critical role in enhancing proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes increased assembly of the 26S proteasome, leading to higher proteasome activity.

O00231

Predicted band size: 47 kDa; Observed band size: 47 kDa

Protein G

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse, Rat

WB: 1:500-2000; ICC/IF: 1:100-500; ELISA: 1:1000-5000

WB, ICC/IF, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG3

Synthesized peptide derived from human protein.AA range:250-350