2. Vitamin D Related/Nuclear Receptor
  3. Pregnane X Receptor (PXR)
  4. Cholic acid-Glu

Cholic acid-Glu is a derivative of Cholic acid (HY-N0324). The abundance of Cholic acid-Glu is increased in Crohn’s disease. Cholic acid-Glu increases PXR activation and significantly increases the expression of the downstream PXR target gene Cyp3a11 in small intestinal organoid tissue.

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Cholic acid-Glu Chemical Structure

Cholic acid-Glu Chemical Structure

CAS No. : 95051-21-1

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Cholic acid-Glu Related Antibodies

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Description

Cholic acid-Glu is a derivative of Cholic acid (HY-N0324). The abundance of Cholic acid-Glu is increased in Crohn’s disease. Cholic acid-Glu increases PXR activation and significantly increases the expression of the downstream PXR target gene Cyp3a11 in small intestinal organoid tissue[1].

Molecular Weight

521.69

Formula

C29H47NO7
CAS No.
SMILES

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(N[C@H](C(O)=O)CCC(O)=O)=O)([H])[C@@]3([H])[C@@](C[C@@H]1O)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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Cholic acid-Glu Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cholic acid-Glu95051-21-1Pregnane X Receptor (PXR)Pregnane X ReceptorCrohn’s diseaseCholic acid derivativeInhibitorinhibitorinhibit

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HY-174300
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