Activated EG3 Tail

Cat. No.: HY-153402 Purity: 99.31%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Activated EG3 Tail can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. It can be used for research of muscular dystrophy.

For research use only. We do not sell to patients.

Activated EG3 Tail Chemical Structure

CAS No. : 1380600-06-5

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

765.85

Formula

C₄₃H₄₇N₃O₁₀

CAS No.

1380600-06-5

Appearance

Solid

Color

White to off-white

SMILES

O=C([C@]1([H])[C@]([C@@]2([H])C[C@]1([H])C=C2)([H])C3=O)N3OC(CCC(OCCOCCOCCOC(N(CC4)CCN4C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (130.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.3057 mL	6.5287 mL	13.0574 mL
5 mM	0.2611 mL	1.3057 mL	2.6115 mL
10 mM	0.1306 mL	0.6529 mL	1.3057 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.31%

Select Batch:

Data Sheet (267 KB) SDS (252 KB)

COA (247 KB) HNMR (305 KB) RP-HPLC (325 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Passini MA, et al. Exon skipping oligomer conjugates for muscular dystrophy. World Intellectual Property Organization, WO2018118599 A1. 2018-06-28.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.3057 mL	6.5287 mL	13.0574 mL	32.6435 mL
	5 mM	0.2611 mL	1.3057 mL	2.6115 mL	6.5287 mL
	10 mM	0.1306 mL	0.6529 mL	1.3057 mL	3.2643 mL
	15 mM	0.0870 mL	0.4352 mL	0.8705 mL	2.1762 mL
	20 mM	0.0653 mL	0.3264 mL	0.6529 mL	1.6322 mL
	25 mM	0.0522 mL	0.2611 mL	0.5223 mL	1.3057 mL
	30 mM	0.0435 mL	0.2176 mL	0.4352 mL	1.0881 mL
	40 mM	0.0326 mL	0.1632 mL	0.3264 mL	0.8161 mL
	50 mM	0.0261 mL	0.1306 mL	0.2611 mL	0.6529 mL
	60 mM	0.0218 mL	0.1088 mL	0.2176 mL	0.5441 mL
	80 mM	0.0163 mL	0.0816 mL	0.1632 mL	0.4080 mL
	100 mM	0.0131 mL	0.0653 mL	0.1306 mL	0.3264 mL