Cofilin Antibody (YA1311)

Cat. No.: HY-P81566: Data Sheet User Guide for Antibodies
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Cofilin Antibody (YA1311) is a non-conjugated IgG antibody, targeting Cofilin 1, with a predicted molecular weight of 19 kDa (observed band size: 19 kDa). Cofilin Antibody (YA1311) can be used for WB, IF-Cell, FC experiment in Human, Mouse, Rat, Monkey background.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

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Description	Cofilin Antibody (YA1311) is a non-conjugated IgG antibody, targeting Cofilin 1, with a predicted molecular weight of 19 kDa (observed band size: 19 kDa). Cofilin Antibody (YA1311) can be used for WB, IF-Cell, FC experiment in Human, Mouse, Rat, Monkey background.
Background	Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. In conjunction with the subcortical maternal complex (SCMC), it plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics. It is required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity). Cofilin plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells. It is also required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Additionally, Cofilin is involved in neural tube morphogenesis and neural crest cell migration (By similarity).
Gene ID	1072 [NCBI]
SwissProt ID	P23528
Synonyms	18 kDa phosphoprotein antibody; CFL 1 antibody; CFL antibody; CFL1 antibody; COF1_HUMAN antibody; Cofilin 1 antibody; Cofilin 1 non muscle antibody; Cofilin antibody; Cofilin non muscle isoform antibody; Cofilin-1 antibody; epididymis secretory protein Li 15 antibody; HEL-S-15 antibody; non-muscle isoform antibody; p18 antibody
Molecular Weight	Predicted band size: 19 kDa; Observed band size:19 kDa
Purity	Protein A affinity purified.
Conjugation	Non-conjugated
Modification	Unmodified
Research Field	Tumor biology
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Monoclonal, Recombinant
Host	Rabbit
Reactivity	Human, Mouse, Rat, Monkey
Dilution Ratio	WB: 1:1,000; IF-Cell: 1:100; FC: 1:200-1:1,000
Application	WB, ICC/IF, FC
Positive Control	Hela cell lysate, HEK-293 cell lysate, MCF-7 cell lysate, MDA-MB-468 cell lysate, K-562 cell lysate, SH-SY5Y cell lysate, HUVEC cell lysate, Jurkat cell lysate, A431 ce
Appearance	Liquid
Formulation	Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	Synthetic peptide within human Cofilin aa 117-166 / 166.
Database	Entrez Gene: 1072 Human ; 12631 Mouse ; 29271 Rat SwissProt: P23528 Human ; P18760 Mouse ; P45592 Rat OMIM: 601442 Human
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

Cofilin Antibody (YA1311) Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cofilin Antibody (YA1311)

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