Search Result

Results for "

Apo-/- mice

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (5) 15-PGDH (1) 5 alpha Reductase (1) 5-HT Receptor (33) AAK1 (1) Acetyl-CoA Carboxylase (3) Acyltransferase (3) ADC Antibody (1) ADC Linker (1) ADC Payload (3) Adenosine Deaminase (1) Adenosine Receptor (13) Adenylate Cyclase (1) Adiponectin Receptor (1) Adrenergic Receptor (14) AIM2 (1) Akt (67) Aldehyde Dehydrogenase (ALDH) (4) Aldose Reductase (2) Amine N-methyltransferase (1) Amino Acid Decarboxylase (2) Amino Acid Derivatives (6) Aminoacyl-tRNA Synthetase (2) Aminopeptidase (5) Aminotransferases (Transaminases) (1) AMPK (30) Amylases (3) Amylin Receptor (1) Amyloid-β (41) Anaplastic lymphoma kinase (ALK) (10) Androgen Receptor (21) Angiotensin Receptor (3) Angiotensin-converting Enzyme (ACE) (5) ANGPTL (1) Annexin A (2) Antibiotic (97) Antibody-Drug Conjugates (ADCs) (4) Antifolate (3) AP-1 (5) Apical Sodium-Dependent Bile Acid Transporter (4) Apolipoprotein (9) Apoptosis (387) Aquaporin (2) Arginase (2) Arrestin (3) Aryl Hydrocarbon Receptor (13) ASCT (3) Atg7 (2) Atg8/LC3 (7) ATM/ATR (3) ATP Synthase (4) AUTACs (1) Autophagy (79) Bacterial (214) Bcl-2 Family (42) Bcr-Abl (2) BCRP (3) Beclin1 (1) Beta-lactamase (9) Beta-secretase (4) Biochemical Assay Reagents (56) BMI1 (1) BMX Kinase (1) Bombesin Receptor (3) Bradykinin Receptor (4) Btk (7) c-Fms (6) c-Kit (3) c-Met/HGFR (17) c-Myc (6) C-type Lectin-like Receptors (CTLRs) (2) Cadherin (1) Calcium Channel (38) Calmodulin (1) CaMK (4) Cannabinoid Receptor (19) Carbonic Anhydrase (5) Carboxylesterase (CES) (2) Carboxypeptidase (1) Casein Kinase (7) Caspase (56) CaSR (1) Cathepsin (4) CCR (2) CD1 (1) CD19 (2) CD20 (1) CD28 (2) CD3 (4) CD38 (1) CD6 (1) CD73 (1) CD74 (1) CDK (33) Ceramidase (2) CFTR (1) CGRP Receptor (1) Chemerin Receptor (1) CHIKV (1) Chloride Channel (2) Cholecystokinin Receptor (5) Cholinesterase (ChE) (31) ClpP (3) CMV (6) Collagen (1) Complement System (6) COMT (1) Constitutive Androstane Receptor (1) COX (30) Cryptochrome (2) CTLA-4 (1) Cuproptosis (3) CX3CR1 (1) CXCR (12) Cyclic GMP-AMP Synthase (3) Cytochrome P450 (37) DAGL (1) DAPK (2) Dengue Virus (4) Deubiquitinase (6) DGK (1) Dihydroorotate Dehydrogenase (4) Dipeptidyl Peptidase (6) Discoidin Domain Receptor (4) DNA Alkylator/Crosslinker (2) DNA Methyltransferase (3) DNA-PK (1) DNA/RNA Synthesis (55) Dopamine Receptor (25) Dopamine Transporter (9) Dopamine β-hydroxylase (1) Drug Derivative (27) Drug Intermediate (5) Drug Isomer (5) Drug Metabolite (22) Drug-Linker Conjugates for ADC (3) Dynamin (2) DYRK (4) E1/E2/E3 Enzyme (8) E3 Ligase Ligand-Linker Conjugates (2) EAAT (4) EBI2/GPR183 (2) EBV (4) EGFR (30) Elastase (2) Endogenous Metabolite (166) Endothelin Receptor (1) Enolase (1) Enterovirus (7) Ephrin Receptor (4) Epigenetic Reader Domain (24) Epoxide Hydrolase (6) ERK (36) Estrogen Receptor/ERR (20) Eukaryotic Initiation Factor (eIF) (6) FAAH (1) FABP (5) Factor Xa (2) Factor XI (1) FAK (8) FAP (2) Farnesyl Transferase (2) Fat Mass and Obesity-associated Protein (FTO) (1) FATP (1) Fatty Acid Synthase (FASN) (4) FBPase (1) Fc Receptor (FcR) (1) Ferroportin (1) Ferroptosis (30) FGFR (10) Filovirus (1) FKBP (1) FLAP (2) Flavivirus (10) FLT3 (15) Fluorescent Dye (22) Formyl Peptide Receptor (FPR) (2) FOXO (2) Free Fatty Acid Receptor (2) Fungal (49) FXR (10) G protein-coupled Bile Acid Receptor 1 (2) G Protein-coupled Receptor Kinase (GRK) (2) G-quadruplex (3) G2A (GPR132) (2) GABA Receptor (21) Galectin (1) Gap Junction Protein (4) GCGR (10) GHSR (1) GLP Receptor (14) Glucocorticoid Receptor (7) Glucokinase (5) Glucosylceramide Synthase (GCS) (1) GLUT (5) Glutaminase (1) Glutathione Peroxidase (17) Glutathione S-transferase (7) Glycosidase (11) Glycosyltransferase (1) GlyT (1) GnRH Receptor (5) GPR119 (6) GPR171 (1) GPR35 (2) GPR52 (1) GPR68 (2) GPR88 (1) GSK-3 (8) Guanylate Cyclase (1) Haspin Kinase (2) HBV (17) HCN Channel (2) HCV (2) HDAC (35) Hedgehog (1) Heme Oxygenase (HO) (4) Herbicide (8) Hexokinase (1) HIF/HIF Prolyl-Hydroxylase (14) Hippo (MST) (1) Histamine Receptor (34) Histone Acetyltransferase (9) Histone Demethylase (10) Histone Methyltransferase (12) HIV (18) HIV Integrase (1) HIV Protease (1) HMG-CoA Reductase (HMGCR) (1) HSP (21) HSV (14) Huntingtin (4) Hydroxycarboxylic Acid Receptor (HCAR) (1) IAP (2) ICMT (1) IFNAR (19) IGF-1R (2) iGluR (27) IKK (18) IKZF Family (3) Imidazoline Receptor (4) IMPDH (1) Indoleamine 2,3-Dioxygenase (IDO) (11) Influenza Virus (26) Insecticide (4) Insulin Receptor (7) Integrin (11) Interleukin Related (111) IRAK (6) IRE1 (2) Isocitrate Dehydrogenase (IDH) (2) Isotope-Labeled Compounds (68) Itk (4) JAK (14) JNK (20) Keap1-Nrf2 (34) Kinesin (3) KLF (2) Lactate Dehydrogenase (10) LAG-3 (3) LDLR (5) Legumain (1) Leukotriene Receptor (2) Ligands for Target Protein for PROTAC (2) LIM Kinase (LIMK) (1) Lipase (4) Lipocalin Family (1) Liposome (20) Lipoxygenase (2) LPL Receptor (5) LRRK2 (5) LXR (3) LYTACs (1) mAChR (9) MAGL (4) MAP3K (3) MAP4K (4) MAPKAPK2 (MK2) (2) MARCKS (2) MARK (1) Mas-related G-protein-coupled Receptor (MRGPR) (5) MCHR1 (GPR24) (2) MDM-2/p53 (29) MEK (7) Melanocortin Receptor (4) Melatonin Receptor (2) MetAP (1) mGluR (20) MHC (6) MicroRNA (3) Microtubule/Tubulin (29) Mineralocorticoid Receptor (1) Mitochondrial Metabolism (16) Mitophagy (6) Mitosis (3) MMP (38) MNK (1) Molecular Glues (3) Monoamine Oxidase (22) Monoamine Transporter (1) Mps1 (1) mTOR (30) Mucin (1) MyD88 (5) Na+/Ca2+ Exchanger (4) Na+/H+ Exchanger (NHE) (6) Na+/K+ ATPase (7) nAChR (24) NADPH Oxidase (3) NAMPT (7) Necroptosis (4) NEDD8-activating Enzyme (3) NEKs (4) Neprilysin (2) Neurokinin Receptor (2) Neuromedin U Receptor (NMUR) (2) Neuropeptide S Receptor (1) Neuropeptide Y Receptor (4) Neurotensin Receptor (2) NF-κB (115) NO Synthase (35) NOD-like Receptor (NLR) (27) Notch (6) Nuclear Factor of activated T Cells (NFAT) (6) Nuclear Hormone Receptor 4A/NR4A (4) Nucleoside Antimetabolite/Analog (6) Oct3/4 (1) OGA (1) Opioid Receptor (27) Orexin Receptor (OX Receptor) (8) Orphan GPCR (2) Orphan Receptor (2) Orthopoxvirus (10) Osteopontin (1) Oxidative Phosphorylation (6) P-glycoprotein (12) P-selectin (2) P2X Receptor (5) P2Y Receptor (3) p38 MAPK (47) p62 (4) p97 (1) PACAP Receptor (2) PAI-1 (1) PAK (4) Parasite (63) PARP (24) PCSK9 (2) PD-1/PD-L1 (16) PDGFR (4) PDHK (2) PDI (3) Penicillin-binding protein (PBP) (4) Peptide-Drug Conjugates (PDCs) (2) PERK (18) Peroxidase Enzyme (1) PGC-1α (1) PGE synthase (7) Phosphatase (14) Phosphodiesterase (PDE) (21) Phospholipase (4) Phosphorylase (1) Photosensitizer (1) Photosystem II (3) PI3K (38) PI4K (1) PI4P5K (1) PIKfyve (1) Pim (8) PKA (15) PKC (18) PKD (7) Platelet-activating Factor Receptor (PAFR) (6) Polo-like Kinase (PLK) (1) Porcupine (1) Potassium Channel (18) PPAR (40) Pregnane X Receptor (PXR) (1) Prion Protein (1) Progesterone Receptor (4) Prolyl Endopeptidase (PREP) (2) Prostaglandin Receptor (15) PROTAC Linkers (5) PROTACs (55) Protease Activated Receptor (PAR) (5) Proteasome (9) Protein Arginine Deiminase (2) Proton Pump (2) Protoporphyrinogen IX oxidase (3) PSMA (10) PTEN (2) PTHR (2) Pyroptosis (11) Pyruvate Kinase (1) Quinone Reductase (3) RAD51 (2) Radionuclide-Drug Conjugates (RDCs) (8) Raf (5) RANKL/RANK (3) RAR/RXR (8) Ras (27) Reactive Oxygen Species (ROS) (105) Reference Standards (161) Renin (1) RET (5) REV-ERB (1) Reverse Transcriptase (2) Ribosomal S6 Kinase (RSK) (4) RIP kinase (8) ROCK (8) ROR (11) ROS Kinase (10) RPE65 (1) RSV (4) RXFP Receptor (1) S100 Protein (2) Salt-inducible Kinase (SIK) (4) SARS-CoV (39) Sec61 (1) Ser/Thr Kinase (2) Ser/Thr Protease (17) Serotonin Transporter (15) SGK (3) SGLT (6) SHP2 (2) Sigma Receptor (11) Sirtuin (14) Small Interfering RNA (siRNA) (18) Smo (1) SOD (17) Sodium Channel (30) Somatostatin Receptor (3) SOS1 (4) SPFH Protein Superfamily (1) Src (8) SRPK (2) STAT (35) Stearoyl-CoA Desaturase (SCD) (9) STING (14) STK33 (1) Succinate Dehydrogenase (1) Survivin (4) Syk (2) TAM Receptor (6) Tau Protein (15) Telomerase (3) TET Protein (1) TGF-beta/Smad (17) TGF-β Receptor (11) Thrombin (2) Thymidylate Synthase (1) Thyroid Hormone Receptor (3) Tie (2) Tissue Factor Pathway Inhibitor (TFPI) (1) TMV (1) TNF Receptor (51) TNK1 (2) Toll-like Receptor (TLR) (46) Topoisomerase (17) Transferrin Receptor (4) Transketolase (1) Transmembrane Glycoprotein (9) TREM receptor (2) Trk Receptor (9) TRP Channel (24) TrxR (3) Tryptophan Hydroxylase (2) TSH Receptor (3) TSPO (1) Tyrosinase (1) URAT1 (2) Urea Transporter (1) Vasopressin Receptor (1) VD/VDR (3) VEGFR (15) Virus Protease (14) WDR5 (2) Wee1 (1) Wnt (13) Xanthine Oxidase (10) YAP (4) YB-1 (1) Zinc Finger Protein (1) α-synuclein (6) β-catenin (5) β-glucuronidase (2) γ-secretase (7)
By Research Areas:	Cancer (1103) Cardiovascular Disease (229) Endocrinology (52) Infection (441) Inflammation/Immunology (741) Metabolic Disease (428) Neurological Disease (647)
Click Chemistry:	ADC Synthesis (1) Labeling and Fluorescence Imaging (1) PROTAC Synthesis (3) Azide (4) Alkynes (11)
Oligonucleotides:	Solvents (1) Preservatives (1) Nucleosides and their Analogs (1) Nucleoside Phosphoramidites (1) Fillers (2) Thymine (1) Rat Pre-designed siRNA Sets (1) Phospholipids (2) siRNA drugs (1) Antisense Oligonucleotides (10) Cholesterol (1) siRNAs (6) Pegylated Lipids (3) U (1) MicroRNAs (1) Aptamers (3) CpG ODNs (2) Mouse Pre-designed siRNA Sets (1) Cationic Lipids (7) Adjuvant (1) Human Pre-designed siRNA Sets (3)

2819

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

217

Peptides

MCE Kits

106

Inhibitory Antibodies

451

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3267A

Apo-Bovine Transferrin	Ferroportin Transferrin Receptor	Neurological Disease
Apo-Bovine Transferrin refers to iron free Transferrin (HY-P3267), serves as Transferrin receptor ligand and mediates iron release from endothelial cells. Apo-Transferrin can directly bind to hephaestin, which can convert Fe ²⁺ to Fe ³⁺. Apo-Transferrin mediates iron efflux most likely in cooperation with ferroportin 1. Apo-Bovine Transferrin can be used in neuroretinal research .

HY-N6677

*β-Apo-8'-carotenal* Apocarotenal	Cytochrome P450	Cancer
β-Apo-8'-carotenal (Apocarotenal), a provitamin A carotenoid, is an inducer of CYPlA1 and CYPlA2 in rat. β-Apo-8'-carotenal is present in many fruits and vegetables .

HY-101953

*β-Apo-13-carotenone* D'Orenone	RAR/RXR	Others
β-Apo-13-carotenone (D'Orenone) is a naturally occurring β-apocarotenoid functioned as an antagonist of RXRα.

HY-P11004

A3-APO	Bacterial Antibiotic	Infection
A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .

HY-P10943

APO-15	Ser/Thr Kinase	Inflammation/Immunology Cancer
APO-15 is a fluorogenic imaging agent targeting phosphatidylserine (PS) exposed on the cell membrane of apoptotic cells. APO-15 can selectively bind to apoptotic cells, enabling staining and imaging of apoptotic cells in a calcium-independent and wash-free manner. APO-15 is promising for research of inflammatory diseases and cancers .

HY-107217

Apo-12'-lycopenal	PPAR	Metabolic Disease
Apo-12'-lycopenal is a Lycopene (HY-N0287) metabolite. Apo-12'-lycopenal promotes adipocyte differentiation and adiponectin secretion via PPAR-γ activation .

HY-N15681

*β-Apo-10'-carotenal* 10'-Apo-β-carotenal	Drug Metabolite	Others
β-Apo-10'-carotenal is a degradation product of β,β-carotene. β-Apo-10'-carotenal can be used in flavor research .

HY-W782321

*β-Apo-12'-carotenal* 12'-Apo-β-carotenal	Drug Derivative	Others
β-Apo-12'-carotenal (12'-Apo-β-carotenal) is a carotenoid derivative. β-Apo-12'-carotenal can be isolated from chili pepper fruits. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-172023

apo-Enterobactin	Bacterial	Infection
apo-Enterobactin is a derivative of Enterobactin (HY-128525). Enterobactin is a bacterial siderophore that promotes iron absorption .

HY-151123

Pelacarsen AKCEA-Apo(a)-LRx; ISIS 681257; TQJ230	Apolipoprotein	Cardiovascular Disease
Pelacarsen (AKCEA-APO(a)-LRx) is a liver-specific antisense oligonucleotide against apolipoprotein(a) that reduces lipoprotein(a) up to 80% with good tolerability .

HY-152857

Muvalaplin LY3473329	LDLR	Cardiovascular Disease
Muvalaplin (LY3473329) is an orally active, selective small molecule inhibitor of lipoprotein (a) (Lp (a)) that disrupts the initial non-covalent interaction between apo(a) and apoB100, preventing the disulphide bond and Lp(a) formation. Muvalaplin reduces the levels of Lp (a) in transgenic mice and in cynomolgus monkeys .

HY-D0313

*Ethyl 8'-apo-caroten-8'-oate*	Fluorescent Dye	Others
Ethyl 8'-apo-caroten-8'-oate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-P5533

CRT	Biochemical Assay Reagents	Cancer
CRT, an iron peptide mimic, can bind to apo-transferrin (apo-Tf). CRT can be used to modify nanoparticles, and enhances drug delivery efficiency .

HY-N15888

Palmitic acid - lissamine rhodamine	Fluorescent Dye	Others
Palmitic acid-lissamine rhodamine is a lissamine rhodamine-labeled Palmitic acid (HY-N0830).

HY-W753387

TopFluor-20:4 PC - IsoPure	Biochemical Assay Reagents	Others
TopFluor-20:4 PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-W408607

N-Benzylacetamidine hydrobromide	NO Synthase	Inflammation/Immunology
N-Benzylacetamidine (hydrobromide) is a acetamidine compound. N-Benzylacetamidine (hydrobromide) is a selective inducible nitric oxide synthase (iNOS) inhibitor with an IC₅₀ of 0.20 μM .

HY-P99299

Lexatumumab HGS-ETR 2; ETR2-ST01	Apoptosis	Cancer
Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research .

HY-W783249

20:4-16:0 PC - IsoPure	Biochemical Assay Reagents	Others
20:4-16:0 PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-N15180

Corynantheidine (-)-Corynantheidine	Opioid Receptor	Neurological Disease
Corynantheidine ((-)-Corynantheidine) is a mu-opioid receptor (MOR) partial agonist that shows MOR-dependent analgesic effects in mice .

HY-P10811

Na2+ - Ca2+ Exchanger inhibitory peptide XIP	Na+/Ca2+ Exchanger	Neurological Disease
Na ⁺-Ca ²⁺ Exchanger inhibitory peptide (XIP) is a Na ⁺-Ca ²⁺ exchanger inhibitor with a K_i of 200 nM. Na ⁺-Ca ²⁺ Exchanger inhibitory peptide inhibits the Na ⁺-dependent Ca ²⁺ uptake and the Na ⁺-dependent Ca ²⁺ efflux of sarcolemmal vesicles in a noncompetitive manner .

HY-W783246

16:0-18:1(n7) PC - IsoPure	Biochemical Assay Reagents	Others
16:0-18:1(n7) PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-W783248

18:1(n10)-16:0 PC - IsoPure	Biochemical Assay Reagents	Others
18:1(n10)-16:0 PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-W725300

18:1(n9)-16:0 PE - IsoPure	Biochemical Assay Reagents	Others
18:1(n9)-16:0 PE-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-W725301

18:1(n9)-16:0 PS - IsoPure sodium	Biochemical Assay Reagents	Others
18:1(n9)-16:0 PS-IsoPure sodium is an isomerically pure mixed-acyl glycerophospholipid.

HY-W783245

16:0-18:1(n10) PC - IsoPure	Biochemical Assay Reagents	Others
16:0-18:1(n10) PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-W783247

18:1(n7)-16:0 PC - IsoPure	Biochemical Assay Reagents	Others
18:1(n7)-16:0 PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-112798

PH-002	Apolipoprotein	Neurological Disease
PH-002 is an inhibitor of *apolipoprotein (apo) E4* intramolecular domain interaction in neuronal cells that could rescue impairments of mitochondrial motility and neurite outgrowth.

HY-109754

Sulopenem etzadroxil PF-03709270	Bacterial Antibiotic	Infection
Sulopenem etzadroxil is an orally active prodrug of the antibiotic Sulopenem (HY-105284). Sulopenem etzadroxil is active in mice infected with Bacillus anthracis .

HY-137440A

Firazorexton hydrate TAK-994	Orexin Receptor (OX Receptor) ERK	Neurological Disease
Firazorexton hydrate (TAK-994) is an orally active and brain-penetrant orexin type 2 receptor (OX2R) selective agonist. Firazorexton hydrate can promote wakefulness and has the potential to improve narcolepsy-like symptoms in mice .

HY-134191

Cryptochrome modulator 1	Cryptochrome	Metabolic Disease
Cryptochrome modulator 1 (Compound 50) is a cryptochrome modulator. Cryptochrome modulator 1 reduces glucose intolerance in diabetic mice .

HY-120872

AJS1669 free acid	Glycosyltransferase	Metabolic Disease
AJS1669 free acid is a potent and orally available glycogen synthase (GS) activator. AJS1669 improves glucose metabolism and reduces body fat mass in mice[1].

HY-N10346A

Gluconapin	Endogenous Metabolite	Cancer
Gluconapin is a precursor of sulforaphane, a potent anticancer isothiocyanate. Gluconapin reduces the increase in plasma triglycerides induced by corn oil in mice .

HY-113878

12-OAHSA	Endogenous Metabolite	Metabolic Disease
12-OAHSA is a component of olive oil. 12-OAHSA has oral activity, and improves glucose homeostasis in insulin resistant obese mice .

HY-138842

DDN	Insulin Receptor Akt ERK	Metabolic Disease
DDN is a selective insulin receptor (Insulin Receptor) activator, an insulin sensitizer, and a glucose-lowering insulin mimetic with oral bioavailability. DDN can directly bind to the receptor kinase domain and induce Akt and ERK phosphorylation, and it can also enhance insulin's effect on glucose uptake. DDN significantly reduces blood glucose levels in wild-type and diabetic ob/ob and db/db mice .

HY-137440

Firazorexton TAK-994 free base	Orexin Receptor (OX Receptor) ERK	Neurological Disease
Firazorexton (TAK-994 free base) is an orally active and brain-penetrant orexin type 2 receptor (OX2R) selective agonist. Firazorexton (TAK-994 free base) can promote wakefulness and has the potential to improve narcolepsy-like symptoms in mice .

HY-153617

FOXO1-IN-3	FOXO	Metabolic Disease
FOXO1-IN-3 is a highly-selective and orally active FOXO1 inhibitor. FOXO1-IN-3 reduces hepatic glucose production in mice. FOXO1-IN-3 improves insulin sensitivity and glucose control in db/db mice without causing weight gain .

HY-162396

P-gp inhibitor 21	P-glycoprotein	Cancer
P-gp inhibitor 21 (Compound 56) is an inhibitor for P-glycoprotein (P-gp) transport, which reverses P-gp-mediated multidrug resistance (MDR) and exhibits antitumor efficacy in mice without significant cytotoxicity .

HY-126426

CBHcy	DNA Methyltransferase	Cardiovascular Disease
CBHcy is an inhibitor for betaine-homocysteine S-methyltransferase (BGMT), with an IC₅₀ of 0.09 μM. CBHcy upregulates the plasma total homocysteine and causes transient hyperhomocysteinemia in mice model .

HY-P11031

CotH3 peptide	Fungal	Infection
CotH3 peptide is a functional peptide unique to Mucorales that binds to the host GRP78 receptor and allows them to invade endothelial cells. CotH3 peptide–targeted monoclonal antibodies protect immunosuppressed mice from mucormycosis caused by R. delemar and other Mucorales. CotH3 peptide also synergizes with antifungal drugs to protect mice with diabetic ketoacidosis (DKA) from R. delemar infection .

HY-P3134

CPN-267	Neuromedin U Receptor (NMUR)	Metabolic Disease
CPN-267 (compound 7b) is a selective neuromedin U receptor 1 (NMUR1) agonist with the EC₅₀ of 0.25 nM. CPN-267 suppresses body weight gain in mice and can be used for study of obesity .

HY-129661

AH 7959	Opioid Receptor	Neurological Disease
AH 7959 is an orally active N-substituted cyclohexyl methyl benzamide compound that has analgesic effects, the oral and subcutaneous ED₅₀ of AH 7959 in mice is greater than 100 mg/kg .

HY-P6053

KK-103	Opioid Receptor	Neurological Disease
KK-103 is a precursor of leucine-enkephalin (Leu-ENK) overcomes high proteolytic instability of Leu-ENK via markedly increased plasma stability in mice that has antinociceptive effect .

HY-P991595

HB-0017	Interleukin Related	Inflammation/Immunology
HB-0017 is a humanized IgG1κ monoclonal antibody inhibitor, targeting IL-17A. HB-0017 inhibits the IL-6 secretion induced by IL-17A with an IC₅₀ of 2.09 nM. HB-0017 significantly decreases ear thickness in Imiquimod (HY-B0180)-induced psoriasis-like mice model and alleviates inflammations in IL-17A-induced arthritis and air pouch mice model. The isotype control for the HB-0017 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-N15859

16:0-LR/18:1/18:1 TG - Lissamine rhodamine	Fluorescent Dye	Others
16:0-LR/18:1/18:1 TG-lissamine rhodamine is a fluorescent lipid.

HY-177297

LCZ960 NVP-LCZ960	Glucokinase	Metabolic Disease
LCZ960 is an orally active glucokinase (GK) activator. LCZ960 stimulates GK activity in hepatocytes in vitro and stimulates glucose uptake in vivo through hepatic GK activation. LCZ960 lowers blood glucose in mice with diet-induced obesity (DIO). LCZ960 maintains normoglycemia and improves glucose tolerance in DIO mice and rats. LCZ960 stimulates glycogen synthase flux and increases hepatic glycogen turnover in rats. LCZ960 induces increased hepatic glycogen recycling. LCZ960 can be used to study high-fat diet-induced obesity and type 2 diabetes .

HY-168365

(±)-Pellotine hydrochloride	Drug Isomer	Neurological Disease
(±)-Pellotine hydrochloride (Compound 2) is an alkaloid, which is found in L. diffusa and L. fricii. (±)-Pellotine hydrochloride decreases locomotor activity and the amount of rapid eye movement (REM) sleep in mice .

HY-169421

Nav1.7-IN-18	Sodium Channel	Cancer
Nav1.7-IN-18 (Compound 31) is a Nav1.7 inhibitor with a K_i value of 4.9 nM and an IC₅₀ of 13 nM, showing analgesic effects in transgenic mice with inherited erythromelalgia (IEM) .

HY-N15182

4-Trehalosamine	Bacterial Drug Derivative	Infection
4-Trehalosamine is a derivative of trehalose with weak antibacterial activity. 4-Trehalosamine shows no toxic effects when injected intravenously into mice at a dose of 625 mg/kg .

HY-16339

N3PT 1 Publications Verification N3-pyridyl thiamine	Transketolase	Cancer
N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor. N3PT is pyrophosphorylated and then binds to transketolase with an K_d value of 22 nM (Apo-TK, transketolase lacking bound thiamine) .

HY-50876

Daporinad 50+ Cited Publications FK866; Apo866	NAMPT Autophagy	Cancer
Daporinad (FK866) is an effective inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase; Nampt) with an IC₅₀ of 0.09 nM.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6677

*β-Apo-8'-carotenal* Apocarotenal	Other Terpenoids other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Cancer	Cytochrome P450
β-Apo-8'-carotenal (Apocarotenal), a provitamin A carotenoid, is an inducer of CYPlA1 and CYPlA2 in rat. β-Apo-8'-carotenal is present in many fruits and vegetables .

HY-N15681

*β-Apo-10'-carotenal* 10'-Apo-β-carotenal	Structural Classification Natural Products Microorganisms Source classification	Drug Metabolite
β-Apo-10'-carotenal is a degradation product of β,β-carotene. β-Apo-10'-carotenal can be used in flavor research .

HY-W782321

*β-Apo-12'-carotenal* 12'-Apo-β-carotenal	Structural Classification Natural Products Capsicum annuum L. Source classification Solanaceae Plants	Drug Derivative
β-Apo-12'-carotenal (12'-Apo-β-carotenal) is a carotenoid derivative. β-Apo-12'-carotenal can be isolated from chili pepper fruits. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-N15888

Palmitic acid - lissamine rhodamine	Structural Classification Lipid	Fluorescent Dye
Palmitic acid-lissamine rhodamine is a lissamine rhodamine-labeled Palmitic acid (HY-N0830).

HY-W753387

TopFluor-20:4 PC - IsoPure	Structural Classification Lipid	Biochemical Assay Reagents
TopFluor-20:4 PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-N15180

Corynantheidine (-)-Corynantheidine	Structural Classification Alkaloids Source classification Rubiaceae Mitragyna speciosa Korth. Plants Indole Alkaloids	Opioid Receptor
Corynantheidine ((-)-Corynantheidine) is a mu-opioid receptor (MOR) partial agonist that shows MOR-dependent analgesic effects in mice .

HY-W783248

18:1(n10)-16:0 PC - IsoPure	Structural Classification Lipid	Biochemical Assay Reagents
18:1(n10)-16:0 PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-W725300

18:1(n9)-16:0 PE - IsoPure	Structural Classification Lipid	Biochemical Assay Reagents
18:1(n9)-16:0 PE-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-W725301

18:1(n9)-16:0 PS - IsoPure sodium	Structural Classification Lipid	Biochemical Assay Reagents
18:1(n9)-16:0 PS-IsoPure sodium is an isomerically pure mixed-acyl glycerophospholipid.

HY-W783245

16:0-18:1(n10) PC - IsoPure	Structural Classification Lipid	Biochemical Assay Reagents
16:0-18:1(n10) PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-W783247

18:1(n7)-16:0 PC - IsoPure	Structural Classification Lipid	Biochemical Assay Reagents
18:1(n7)-16:0 PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.

HY-N10346A

Gluconapin	Structural Classification Brassica rapa L. Ketones, Aldehydes, Acids Source classification Plants Brassicaceae	Endogenous Metabolite
Gluconapin is a precursor of sulforaphane, a potent anticancer isothiocyanate. Gluconapin reduces the increase in plasma triglycerides induced by corn oil in mice .

HY-N15859

16:0-LR/18:1/18:1 TG - Lissamine rhodamine	Structural Classification Lipid	Fluorescent Dye
16:0-LR/18:1/18:1 TG-lissamine rhodamine is a fluorescent lipid.

HY-N15182

4-Trehalosamine	Structural Classification Microorganisms Antibiotics Source classification	Bacterial Drug Derivative
4-Trehalosamine is a derivative of trehalose with weak antibacterial activity. 4-Trehalosamine shows no toxic effects when injected intravenously into mice at a dose of 625 mg/kg .

HY-125721

Tetranactin	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Fungal Bacterial Antibiotic
Tetranactin is an orally active antibiotic that has insecticidal properties and can inhibit the growth of Gram-positive bacteria and plant pathogenic fungal in vitro. Tetranactin LD₅₀ for intraperitoneal injection in mice is greater than 300 mg/kg, and the LD₅₀ is greater than 15,000 mg/kg .

HY-N10171

GB-2a	Structural Classification Flavonoids Source classification Rubiaceae Plants Gardenia jasminoides Ellis Other Flavonoids	Others
GB-2a is a bioflavonoids that can be isolated from Rheedia gardneriana. GB-2a has significant analgesic activity in mice with 58.9% inhibition .

HY-129577

Aplysin	Structural Classification Natural Products Animals Source classification	Necroptosis
Aplysin is a brominated sesquiterpene with an isoprene backbone that exhibits hepatoprotective, immunomodulatory, and antitumor activities. Aplysin effectively prevents spontaneous pancreatic necrosis and inflammatory responses in NOD mice .

HY-N8210

Homoeriodictyol	Structural Classification Flavonoids other families Classification of Application Fields Flavonones Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Drug Metabolite Autophagy Apoptosis Reactive Oxygen Species (ROS) Keap1-Nrf2 MMP Caspase PARP MDM-2/p53
Homoeriodictyol is an orally active, bitter-tasting flavanone that can penetrate the blood-brain barrier. Homoeriodictyol enhances synaptic-related protein expression through NCOA4-mediated ferritin autophagy. Homoeriodictyol improves memory impairment in mice by inhibiting the NLRP3 inflammasome. Homoeriodictyol protects human endothelial cells from oxidative damage by activating Nrf2 and inhibiting mitochondrial dysfunction. Homoeriodictyol enhances ROS activity and induces apoptosis, exhibiting anticancer effects. Homoeriodictyol inhibits the survival and migration of androgen-resistant prostate cancer cells in vitro. Homoeriodictyol exerts antinociceptive activity in mice in vivo .

HY-N2953

Borapetoside E	Structural Classification Natural Products Source classification Plants Menispermaceae Tinospora crispa (L.) Hook. f. et Thoms	Fatty Acid Synthase (FASN)
Borapetoside E can be isolated from T. crispa. Borapetoside E improves hyperglycemia, insulin resistance, hepatic steatosis, hyperlipidemia, and oxygen consumption in obese mice. Borapetoside E also inhibits SREBPs expression in the liver and adipose tissue .

HY-W654264

2-Methylbutyrylcarnitine chloride	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite Integrin
2-Methylbutyrylcarnitine (chloride) is a gut microbial metabolite which binds to integrin α2β1 in platelets, potentiating cytosolic phospholipase A2 (cPLA2) activation and platelet hyperresponsiveness. 2-Methylbutyrylcarnitine (chloride) enhances platelet hyperreactivity and thrombus formation in mice. 2-Methylbutyrylcarnitine (chloride) is a branched-chain acylcarnitine .

HY-113365

Cholestenone 4-Cholesten-3-one	Structural Classification Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholestenone (4-cholesten-3-one) is an orally available antimicrobial agent that is metabolized primarily in the liver as an intermediate oxidation product of cholesterol. Cholestenone inhibits human dermal fibroblast migration and fights Helicobacter pylori infection in vitro and in mouse models by inhibiting cholesterol-α-D-glucopyranoside (CGL). Cholestenone also alleviates metabolic disorders caused by obesity in db/db mice .

HY-B1192

Estradiol benzoate 10+ Cited Publications β-Estradiol 3-benzoate; 17β-Estradiol 3-benzoate	Classification of Application Fields Disease Research Fields Cancer	Estrogen Receptor/ERR HBV Bcl-2 Family
Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice .

HY-N1503

Methyl deacetylasperulosidate 6α-Hydroxygeniposide; Deacetylasperulosidic acid methyl ester	Structural Classification Iridoids Classification of Application Fields Terpenoids Source classification Rubiaceae Metabolic Disease Plants Disease Research Fields Hedyotis diffusa Willd.	Others
Methyl deacetylasperulosidate is an iridoid and shows purgative effects in mice and lowers the blood glucose level in normal mice .

HY-P2818

Alkaline phosphatase, Bovine intestine 1 Publications Verification Apase	Structural Classification Natural Products Animals Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Endogenous Metabolite Glutathione Peroxidase Bacterial
Alkaline phosphatase, Bovine intestine (Apase) is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Bovine intestine reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Bovine intestine improves survival rate of mice infected with E. coli. Alkaline phosphatase, Bovine intestine improves TNBS-induced colon inflammation .

HY-N15721

Tryptophan-cholic acid Trp-CA	Triterpenes Structural Classification Terpenoids Source classification Endogenous metabolite	Orphan GPCR
Tryptophan-cholic acid (Trp-CA) is a microbial amino-acid-conjugated bile acid, serving as an endogenous ligand and agonist of the orphan G protein-coupled receptor (GPCR) MRGPRE. Tryptophan-cholic acid activates MRGPRE, promoting the secretion of glucagon-like peptide-1 (GLP-1) through the Gs-cAMP and β-arrestin-1-ALDOA signaling pathways, thereby improving glucose tolerance in diabetic mice. Tryptophan-cholic acid is promising for research of type 2 diabetes .

HY-112234

L-Sepiapterin Sepiapterin	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
L-Sepiapterin (Sepiapterin) is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L-Sepiapterin improves endothelial dysfunction in small mesenteric arteries from db/db mice, and induces angiogenesis. L-Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70 ^S6K-dependent VEGFR-2 expression .

HY-N16374

Mazethramycin B	Structural Classification Microorganisms Antibiotics Source classification	Antibiotic Bacterial Fungal
Mazethramycin B (Compound II) is an antitumor antibiotic. Mazethramycin B can be isolated from the Streptomyces thioluteusM ME561-L4. Mazethramycin B has a broad-spectrum antimicrobial activity (such as MICs of 1.56 and 6.25 μg/mL for the bacteria Bacillus subtilis PCI 219 and the fungus Candida pseudotropicalis, resepectively). Mazethramycin B significantly increases survival in L1210 leukemia mice model .

HY-N1503R

Methyl deacetylasperulosidate (Standard) 6α-Hydroxygeniposide (Standard); Deacetylasperulosidic acid methyl ester (Standard)	Structural Classification Iridoids Terpenoids Source classification Rubiaceae Plants Hedyotis diffusa Willd.	Reference Standards Others
Methyl deacetylasperulosidate (Standard) is the analytical standard of Methyl deacetylasperulosidate. This product is intended for research and analytical applications. Methyl deacetylasperulosidate is an iridoid and shows purgative effects in mice and lowers the blood glucose level in normal mice .

HY-N7515

Pinocembrin chalcone 2',4',6'-Trihydroxychalcone	Structural Classification Chalcones Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	Bacterial AMPK
Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound from Helichrysum Trilineatum. Pinocembrin chalcone facilitates AMP-activated protein kinase (AMPK) activation, improves glucose tolerance, increases muscle FAO and reduces fat accumulation in the liver and skeletal muscles in high-fat diet-induced (HFD) diabetic mice. Pinocembrin chalcone is promising for research of gastric ulcers and diabetes .

HY-N14941

Phleomycin G	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Phleomycin G is a heteropeptide antibiotic. Phleomycin G has anti-Gram-positive bacteria, negative bacteria and mycobacterium effects. Phleomycin G extends the survival time of mice transplanted with Ehrman's ascites cancer. Phleomycin G inhibits airy entity carcinoma in mice .

HY-N14586

Roridin J	Structural Classification Natural Products Microorganisms Source classification	Others
Roridin J is a macrocyclic trichothecene and has anti-leukemia effect in mice .

HY-N0260

Epmedin C 5 Publications Verification Epimedin-C; Baohuoside-VI	Flavonols Flavonoids Monophenols Classification of Application Fields Source classification Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Disease Research Fields Inflammation/Immunology	Others
Epmedin C, a natural product, has estrogen-like effects for ovariectomized mice.

HY-N10279

Gymconopin C	Infection other families Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields	Others
Gymconopin C shows an antiallergic effect on ear passive cutaneous anaphylaxis reactions in mice.

HY-N13293

Isopaynantheine 3-Isopaynantheine	Structural Classification Alkaloids Other Alkaloids Source classification Rubiaceae Mitragyna speciosa Korth. Plants	Opioid Receptor
Isopaynantheine (3-Isopaynantheine), an alkaloid, is an opioid. Isopaynantheine has antinociceptive activity in mice.

HY-14393

Emodin 25+ Cited Publications Frangula emodin	Structural Classification Classification of Application Fields Polygonaceae Source classification Plants Endogenous metabolite Quinones Human Gut Microbiota Metabolites Microorganisms Rheum palmatum L. Anthraquinones Phenols Polyphenols Disease Research Fields Cancer	SARS-CoV Casein Kinase Autophagy 11β-HSD
Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

HY-N14887

Phleomycin E	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Phleomycin E is a heteropeptide antibiotic. Phleomycin E has anti-Gram-positive bacteria, negative bacteria and mycobacterium effects. Phleomycin E extends the survival time of mice transplanted with Ehrman's ascites cancer. Phleomycin E inhibits airy entity carcinoma in mice with an IC₅₀ of 0.31 μg/mL .

HY-14608R

L-Glutamic acid (Standard)	Structural Classification Microorganisms Source classification Disease markers Endocrine diseases Amino acids Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder Cancer	Reference Standards Endogenous Metabolite iGluR Ferroptosis Apoptosis
L-Glutamic acid (Standard) is the analytical standard of L-Glutamic acid. This product is intended for research and analytical applications. L-Glutamic acid is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid can be used in the study of neurological diseases . IC₅₀ & Target:DA . In Vitro: L-Glutamic acid (120, 500, 750, 1000 mg/dL) can reduce the harmful effect of lithium on the embryonic development of Xenopus Xenopus . L-Glutamic acid (2, 5, 10, 20 mM, 24-48 h) can induce neuroexcitotoxicity in neuroblastoma . In Vivo: L-Glutamic acid (3 g/kg, subcutaneous injection) can promote excitotoxic degeneration of retinal ganglion cells in mice . L-Glutamic acid (750 mg/kg, intraperitoneal injection) can reduce and inhibit oxidative stress induced by chlorpyrifos (CPF) in rats .

HY-N7394

Galbacin (3S)-Zuonin A	Structural Classification Natural Products Virola surinamensis (Rol. ex Rottb.) Warb. Source classification Myristicaceae Plants	AMPK
Galbacin ((3S)-Zuonin A), the epimer of (-)-Zuonin A (HY-N7394A), is a AMPK activator. Galbacin can be isolated from Myristica fragrans (nutmeg). Galbacin stimulates AMPK enzyme in differentiated C2C12 cells. Galbacin also has anticancer activity, and inhibits the proliferation of lymphocyte and tumor cells. Galbacin prevents weight gain in diet-induced mice model. Galbacin can be used for metabolic syndrome (including obesity and type-2 diabetes) and caners research .

HY-N3098

Pelirine	Apocynaceae Rauvolfia verticillata (Lour.) Baill. Structural Classification Alkaloids Source classification Plants Indole Alkaloids	Others
Pelirine is an alkaloid isolated from R. perakensis and causes death in mice at concentrations of 100 mg/kg and above .

HY-N9794

Isoboldine	Structural Classification Alkaloids Piperidine Alkaloids Source classification Phenols Polyphenols Plants Lauraceae Lindera aggregata (Sims) Kosterm.	Others
Isoboldine is a pyridine alkaloid. Isoboldine effectively alleviates inflammation and joint destruction in collagen-induced arthritis in mice .

HY-19696B

Tauroursodeoxycholate dihydrate 75+ Cited Publications Tauroursodeoxycholic acid dihydrate; TUDCA dihydrate; UR 906 dihydrate	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	Caspase Apoptosis Endogenous Metabolite IRE1 NF-κB JNK Reactive Oxygen Species (ROS) Akt
Tauroursodeoxycholate dehydrate is an orally active taurine conjugate of Ursodeoxycholic acid (HY-13771). Tauroursodeoxycholate dehydrate inhibits caspase-3/7, Apoptosis, IRE1α/TRAF2/NF-κB, prevents JNK phosphorylation, inhibits ROS generation, and activates Akt signaling. Tauroursodeoxycholate dehydrate prevents cataract formation, reduces renal tubular damage in type 2 diabetic mice, reduces I/R injury in liver, and inhibits intestinal inflammation and barrier disruption in nonalcoholic fatty liver disease .

HY-N0204

Pulchinenoside A Anemoside A3	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Ranunculaceae Other Diseases Plants Disease Research Fields Pulsatilla chinensis (Bunge) Regel	iGluR
Pulchinenoside A is a natural triterpenoid saponin that enhances synaptic plasticity in the adult mouse hippocampus and facilitates spatial memory in adult mice.

HY-N0700

alpha-Asarone 2 Publications Verification α-Asarone; trans-Asarone	Acorus tatarinowii Schott Structural Classification Simple Phenylpropanols Araceae Source classification Phenylpropanoids Plants	GABA Receptor
alpha-Asarone (α-Asarone) is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.

HY-N10196

Cerebroside D	Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Inflammation/Immunology	Endogenous Metabolite
Cerebroside D, a glycoceramide compound, improves experimental colitis in mice with multiple targets against activated T lymphocytes .

HY-N10424

Brazilein	Structural Classification Classification of Application Fields Leguminosae Caesalpinia sappan L. Source classification Phenols Polyphenols Pigments Plants Inflammation/Immunology Disease Research Fields Food Research	Apoptosis
Brazilein is an important immunosuppressive component isolated from Caesalpinia sappan L. Brazilein induces apoptosis in mice spleen lymphocytes .

HY-N16371

6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Endogenous Metabolite
6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid (Compound MC-1), an isocoumarin, is a metabolite of Cytogenin (HY-19606). 6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid has anti-angiogenic activity in S-180 implanted dorsal air sac mice model. 6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid also modifies collagen-induced arthritis. 6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid can be used for cancers and inflammatory diseases research .

HY-122916

7-Acetyllycopsamine	Alkaloids other families Pyrrole Alkaloids Classification of Application Fields Source classification Plants Disease Research Fields Inflammation/Immunology	Others
7-Acetyllycopsamine, a pyrrolizidine alkaloid, is a mild hepatotoxin. 7-Acetyllycopsamine can induce liver inflammation in mice .

HY-N13614

Centaurein	Structural Classification Flavonoids Flavones Source classification Amburana cearensis (Allemão) A.C.Sm. Plants Compositae	Bacterial IFNAR Nuclear Factor of activated T Cells (NFAT) NF-κB
Centaurein, a flavonoid, is an IFN-γ promoter enhancer. Centaurein up-regulates the activity of NFAT and NF-κB enhancers. Centaurein increases the IFN-γ expression in T and NK cells and the serum IFN-γ level in mice. Centaureidin completely relaxes the contractions in intact rat aortic rings. Centaurein effectively protects mice against Listeria infection ^[1][2][3][4].

HY-W009688

Dibutyl maleate	Natural Products Rheum palmatum L. Classification of Application Fields Polygonaceae Source classification Plants Inflammation/Immunology Disease Research Fields	Drug Intermediate
Dibutyl maleate, the diester of the Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. Dibutyl maleate can enhance contact sensitization to Fluorescein isothiocyanate in mice .

HY-113354R

Anserine (Standard)	Structural Classification Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Nervous System Disorder Endogenous metabolite	Reference Standards Endogenous Metabolite
Anserine (Standard) is the analytical standard of Anserine. This product is intended for research and analytical applications. Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice[1][2].

Cat. No.	Product Name	Chemical Structure

HY-D0195S

Acesulfame-d4 potassium
Acesulfame-d₄ potassium is the deuterium labeled Acesulfame (potassium) (HY-D0195) . Acesulfame potassium is an artificial sweetener. Acesulfame potassium (long-term) affects cognitive functions, potentially via altering neuro-metabolic functions in mice .

HY-B0448S

Phenytoin-d10
Phenytoin-d₁₀ is the deuterium labeled Phenytoin. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice .

HY-137315S

TML-6-d3
TML-6-d₃ is the deuterium labeled TML-6. TML-6, an orally active curcumin derivative, inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 can upregulate Apo E, suppress NF-κB and mTOR, and increase the activity of the anti-

HY-B0168AS

Milnacipran-d5 hydrochloride

Milnacipran-d₅ hydrochloride is deuterium labeled Milnacipran hydrochloride (HY-B0168A). Milnacipran hydrochloride is an orally active Serotonin (HY-B1473A) and Norepinephrine (HY-13715) reuptake inhibitor. Milnacipran hydrochloride inhibits monoamine transporters, especially the norepinephrine transporter and the serotonin transporter (K_i values of 31 and 8.5 nM, respectively). Milnacipran hydrochloride inhibits pERK1/2 activation. Milnacipran hydrochloride has antidepressant, anxiolytic and analgesic properties. Milnacipran hydrochloride inhibits biting behavior in mice. Milnacipran hydrochloride can be used in the study of major depressive disorder, anxiety disorders, and neuropathic pain (e.g., fibromyalgia) .

HY-B2046S

Simazine-d10
Simazine-d₁₀ is the deuterium labeled Simazine (HY-B2046). Simazine is a triazine herbicide. Simazine is widely used in agriculture, potted plant and tree production. In addition, Simazine can induce the apoptosis of immune cells in the spleen of mice and inhibit the proliferation of B cells and T cells in mice .

HY-B1198S

Piperonyl butoxide-d9
Piperonyl butoxide-d₉ is the deuterium labeled Piperonyl butoxide.Piperonyl butoxide (ENT-14250) is a pesticide synergist and food additive. Piperonyl butoxide has adverse effects on reproduction, development and behavior in mice. Piperonyl butoxide can activate c-Jun and ATF-2 in mouse hepatocytes. Piperonyl butoxide is a liver cancer carcinogen in rats and mice .

HY-175318S

p53 Activator 15

p53 Activator 15 (Compound 2) is an orally active p53 activator. p53 Activator 15 enhances the bind ability of p53 Y220C to DNA and significantly suppresses cancer cells proliferation (IC₅₀: 58  nM for NUGC-3 cells), without inhibitory activity against CYP enzyme. p53 Activator 15 potently inhibits tumor growth in NUGC-3 xenograft mice model. p53 Activator 15 has a broad-spectrum anti-cancer activity, such as breast, stomach and lung cancer .

HY-124412S

Paynantheine-d3
Paynantheine-d₃ is a deuterium labeled Paynantheine. Paynantheine is an alkaloid that can be isolated from Mitragyna speciosa. Paynantheine can decrease alcohol intake in mice .

HY-109044S

Tapinarof-d5
Tapinarof-d₅ (WBI-1001-d₅) is deuterium labeled Tapinarof. Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC₅₀ of 13 nM. Tapinarof resolves skin inflammation in mice .

HY-W744578

Taurolidine-d6
Taurolidine-d₆ is the deuterium labeled Taurolidine (HY-W011522). Taurolidine is a potent antimicrobial and anticancer agent. Taurolidine inhibits cell proliferation. Taurolidine induces apoptosis and autophagy. Taurolidine rescues mice from sepsis-associated lethality .

HY-109506S1

DPPC-d9
DPPC-d₉ is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers . DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice .

HY-109506S

DPPC-d62
DPPC-d₆₂ is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers . DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice .

HY-109506S3

DPPC-d9-1
DPPC-d₉-1 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers . DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice .

HY-B0534S1

Moclobemide-d4
Moclobemide-d₄ is deuterium labeled Moclobemide. Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC₅₀ of 6.061 μM for hMAO-A .Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice.

HY-169222S

RORγ/DHODH-IN-2
RORγ/DHODH-IN-2 (Compound 1311) is an orally active dual inhibitor of RORγ/DHODH with IC₅₀ values of 11.9 nM and 90 nM, respectively. RORγ/DHODH-IN-2 exhibits antiviral activity by inhibiting the activity of SARS-CoV-2, HCMV, HAdV5, and MPXV, with IC₅₀ values of 27 nM, 20 nM, 9.1 nM, and 1.8 nM, respectively .

HY-N3312S

Matairesinol-d6
Matairesinol-d₆ is the deuterium labeled Matairesinol. Matairesinol confers anti-allergic effects in an allergic dermatitis mouse model. DfE-induced changes in IL-4 and IFN-γ mRNA expression in the ears of NC/Nga mice were reversed by matairesinol application .

HY-145119S

Mindeudesivir
GS-621763-d₁ is the deuterium labeled GS-621763 (HY-145119) . GS-621763, an orally bioavailable proagent of GS-441524, shows antiviral activity against SARS-CoV-2 pathogenesis in mice .

HY-B0448S1

Phenytoin-15n2,13c
Phenytoin- ¹⁵N₂, ¹³C is the ¹³C and ¹⁵N labeled Phenytoin . Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice .

HY-14447S1

Bilastine-d4
Bilastine-d₄ is deuterium labeled Bilastine. Bilastine is an oral histamine H1-receptor antagonist. Bilastine can be used for allergic rhinitis and urticaria studies, and it also improves diabetic nephropathy in mice, showing safety for the central nervous system .

HY-B0448S2

Phenytoin-d5
Phenytoin-d₅ (5,5-Diphenylhydantoin-d₅) is deuterium labeled Phenytoin. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na ⁺ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice .

HY-B1946S

Dimethoate-d6
Dimethoate-d₆ is the deuterium labeled Dimethoate. Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active acetylcholinesterase inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice .

HY-N6608S

Physostigmine-d3
Physostigmine-d₃ is the deuterium labeled Physostigmine. Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning .

HY-109120S

Odevixibat-d5
Odevixibat-d₅ is deuterated labeled Odevixibat (HY-109120). Odevixibat (A4250) is a selective and orally active ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor. Odevixibat decreases cholestatic liver and bile duct injury in mice model. Odevixibat has the potential for the treatment of primary biliary cirrhosis .

HY-P0009S1

Cetrorelix-d10
Cetrorelix-d₁₀ (SB-75-d₁₀) is deuterium labeled Cetrorelix. Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice .

HY-113486S1

lathosterol-d7
lathosterol-d₇ is deuterium labeled Lathosterol (HY-113486). Lathosterol is a plant sterol and cholesterol-like molecule. Lathosterol increases antioxidant enzymes (such as SOD, CAT, and GSH) and decreases LDH. Lathosterol has a hepatoprotective effect on mice with acetaminophen (HY-66005)-induced liver injury ^{^.}

HY-B0534S

Moclobemide-d8
Moclobemide-d₈ (Ro111163-d₈) is the deuterium labeled Moclobemide. Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC₅₀ of 6.061 μM for hMAO-A .Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice.

HY-B0149S3

Tranexamic acid-13C2,15N
Tranexamic acid- ¹³C₂, ¹⁵N (Cyclocapron- ¹³C₂, ¹⁵N) is the ¹³C₂ and ¹⁵N labeled Tranexamic acid. Tranexamic acid is an antifibrinolytic agent that alleviates liver damage and fibrosis in mouse models of chronic bile duct injury .

HY-165677S

C22 Galactosylceramide-d4
C22 Galactosylceramide-d₄ is deuterium labeled C22 Galactosylceramide. C22 Galactosylceramide is a sphingolipid present in the central nervous system, exhibiting elevated levels in the spinal cord of mice on a methionine-restricted diet, while not affecting the brain or liver; furthermore, it has been identified in the postmortem hippocampus of Alzheimer's disease patients .

HY-109120S1

Odevixibat-13C6
Odevixibat- ¹³C₆ is ¹³C labeled Odevixibat (HY-109120). Odevixibat (A4250) is a selective and orally active ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor. Odevixibat decreases cholestatic liver and bile duct injury in mice model. Odevixibat has the potential for the treatment of primary biliary cirrhosis .

HY-B1002S

Oxolinic acid-d5
Oxolinic acid-d₅ is the deuterium labeled Oxolinic acid. Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice .

HY-W012481S

Nirvanol-d5
Nirvanol-d₅ (Ethylphenylhydantoin-d₅) is deuterium labeled Nirvanol (HY-W012481) . Nirvanol (Ethylphenylhydantoin) is a metabolite of Mephenytoin (HY-B1184) that exerts anticonvulsant effects in the maximal electroshock (M.E.S.) seizure model in mice. Nirvanol shows potential for research in epilepsy-related neurological disorders .

HY-156856S

FL118-14-Propanol-d5
FL118-14-Propanol-d₅ is the deuterium labeled FL118-14-Propanol (HY-156856). FL118-14-Propanol is a FL118 derivative. FL118-14-Propanol synthesized ADC molecule has good anti-tumor effect in mice .

HY-113354S

Anserine-d4
Anserine-d₄ is the deuterium labeled Anserine. Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice .

HY-100442S

Paquinimod-d5
Paquinimod-d5 is a deuterated analog of Paquinimod (HY-100442). Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice .

HY-100442S1

Paquinimod-d5-1
Paquinimod-d5-1 is a deuterated analog of Paquinimod (HY-100442). Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice .

HY-109506S2

(Rac)-DPPC-d6
(Rac)-DPPC-d6 is a deuterated labeled DPPC . DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-101064S3

Fmoc-leucine-d10
Fmoc-leucine-d₁₀ is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity .

HY-101064S2

Fmoc-leucine-d3
Fmoc-leucine-d₃ is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity .

HY-109506S9

DPPC-13C2
DPPC-13C2 is a deuterated labeled DPPC . DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-113354S1

Anserine-d4 hydrochloride

Anserine-d₄ hydrochloride is the deuterium labeled Anserine (HY-113354). Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice .

HY-B2010S

Fomesafen-d3

Fomesafen-d₃ is the deuterium-labeled Fomesafen (HY-B2010). Fomesafen is an orally active herbicide. Fomesafen inhibits protoporphyrinogen oxidase (PPO). Fomesafen induces Apoptosis and increases ROS. Fomesafen exhibits developmental toxicity, immunotoxicity, and neurotoxicity. It induces precancerous lesions in the liver and hepaturoporphyria in mice. Fomesafen is used to control broadleaf weeds in soybean fields, rubber plantations, and orchards .

HY-B1794S

Thiethylperazine-d3
Thiethylperazine-d₃ is the deuterium labeled Thiethylperazinee (HY-B1794). Thiethylperazine, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine has anti-emetic, antipsychotic and antimicrobial effects .

HY-W711852

Benzamide-d5

Benzamide-d₅ (Benzenecarboxamide-d₅) is deuterium labeled Benzamide. Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature .

HY-109506S10

DPPC-13C3
DPPC- ¹³C₃ (129Y83- ¹³C) is the ¹³C-labeled DPPC (HY-109506). DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-N9484S

Menthofuran-13C2

Menthofuran- ¹³C₂ is ¹³C labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca ⁺⁺ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice .

HY-B0973S

Dibenzothiophene-d8

Dibenzothiophene-d₈ is the deuterium labeled Dibenzothiophene (HY-B0973). Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with K_m of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone (HY-114740). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms .

HY-145119AS

Mindeudesivir hydrobromide
Mindeudesivir (JT001; VV116; GS-621763-d₁) hydrobromide is a deuterated version of Remdesivir (HY-104077), a highly orally active nucleoside antiviral against SARS-CoV-2 and respiratory syncytial virus (RSV). Mindeudesivir hydrobromide retains the antiviral activity of Remdesivir against COVID-19, and is the first domestically produced deuterium targeting the COVID-19 .

HY-W010243S

Methylisothiazolinone-d3 hydrochloride

Methylisothiazolinone-d₃ hydrochloride is the deuterium labeled Methylisothiazolinone hydrochloride (HY-W010243). Methylisothiazolinone hydrochloride is a bacterial and fungal inhibitor and preservative, as well as a sensitizer. Methylisothiazolinone hydrochloride can activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce apoptosis and inflammatory response. Methylisothiazolinone hydrochloride can promote the development of atopic dermatitis in mice by disrupting Th2/Th17 related immune responses. Methylisothiazolinone hydrochloride can cause mitochondrial damage in the endothelium of rat cerebral blood vessels .

HY-W778335

Dimethyl Phthalate-13C2

Dimethyl Phthalate- ¹³C₂ (DMP- ¹³C₂) is the ¹³C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats .

HY-P0119S

Lixisenatide (Leu-13C6,15N) TFA

Lixisenatide (Leu- ¹³C₆, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled Lixisenatide (HY-P0119). Lixisenatide is a GLP-1 receptor agonist. Lixisenatide inhibits the inflammatory response through down regulation of proinflammatory cytokines, and blocks of cellular signaling pathways. Lixisenatide decreases atheroma plaque size and instability in Apoe ^?/? Irs ^2+/? mice by reprogramming macrophages towards an M2 phenotype, which leads to reduced inflammation .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks