1. Stem Cell/Wnt TGF-beta/Smad
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  3. PKI 14-22 amide,myristoylated

PKI 14-22 amide,myristoylated is a potent cAMP-dependent PKA inhibitor. PKI 14-22 amide,myristoylated reduces the IgG-mediated phagocytic response and also inhibits neutrophil adhesion.

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PKI 14-22 amide,myristoylated Chemical Structure

PKI 14-22 amide,myristoylated Chemical Structure

CAS No. : 201422-03-9

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1 mg USD 150 In-stock
5 mg USD 450 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

PKI 14-22 amide,myristoylated is a potent cAMP-dependent PKA inhibitor. PKI 14-22 amide,myristoylated reduces the IgG-mediated phagocytic response and also inhibits neutrophil adhesion[1].

Molecular Weight

1209.49

Formula

C53H100N20O12

CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

Myristoyl-GRTGRRNAI-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (41.34 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8268 mL 4.1340 mL 8.2679 mL
5 mM 0.1654 mL 0.8268 mL 1.6536 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.8268 mL 4.1340 mL 8.2679 mL 20.6699 mL
5 mM 0.1654 mL 0.8268 mL 1.6536 mL 4.1340 mL
10 mM 0.0827 mL 0.4134 mL 0.8268 mL 2.0670 mL
15 mM 0.0551 mL 0.2756 mL 0.5512 mL 1.3780 mL
20 mM 0.0413 mL 0.2067 mL 0.4134 mL 1.0335 mL
25 mM 0.0331 mL 0.1654 mL 0.3307 mL 0.8268 mL
30 mM 0.0276 mL 0.1378 mL 0.2756 mL 0.6890 mL
40 mM 0.0207 mL 0.1033 mL 0.2067 mL 0.5167 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PKI 14-22 amide,myristoylated
Cat. No.:
HY-P1291
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