2. Immunology/Inflammation
  3. Interleukin Related
  4. NI-1201

NI-1201 is a monoclonal antibody that targets, in the human IL-6R sequence, the epitope recognized by 25F10 for mice. NI-1201 inhibits both IL-6 cis- and trans-signaling. NI-1201 targets site IIb of hIL-6R. NI-1201 inhibits gp130 binding to IL-6R.

For research use only. We do not sell to patients.

NI-1201 Chemical Structure

NI-1201 Chemical Structure

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NI-1201 Related Antibodies

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Description

NI-1201 is a monoclonal antibody that targets, in the human IL-6R sequence, the epitope recognized by 25F10 for mice. NI-1201 inhibits both IL-6 cis- and trans-signaling. NI-1201 targets site IIb of hIL-6R. NI-1201 inhibits gp130 binding to IL-6R[1].

IC50 & Target

IL-6Ra/CD126
Gene ID

3570  [NCBI]

Accession
Target

IL-6Ra/CD126
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
SMILES

N/A
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NI-1201 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NI-1201TZLS-501NI1201NI 1201TZLS501TZLS 501Interleukin RelatedILInhibitorinhibitorinhibit

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NI-1201
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