2. Others Neuronal Signaling Protein Tyrosine Kinase/RTK JAK/STAT Signaling Epigenetics Stem Cell/Wnt Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reference Standards Monoamine Oxidase JAK STAT NO Synthase IKK Cytochrome P450
  4. Desmethoxyyangonin (Standard)

Desmethoxyyangonin (Standard)  (Synonyms: Demethoxyyangonin (Standard); 5,6-Dehydrokavain (Standard))

Cat. No.: HY-N0918R Purity: ≥98%
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Desmethoxyyangonin (Standard) is one of the six major kavalactones found in the Piper methysticum (kava) plant. Desmethoxyyangonin (Standard) is a selective inhibitor of monoamine oxidase-B (MAO-B) (IC50: 0.123  µM). Desmethoxyyangonin (Standard) exerts anti-inflammatory effects by inhibiting Jak2/STAT3 and IKK signaling pathways. Desmethoxyyangonin (Standard) induces CYP3A23 expression and leads to skeletal muscle relaxation.

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Desmethoxyyangonin (Standard) Chemical Structure

Desmethoxyyangonin (Standard) Chemical Structure

CAS No. : 15345-89-8

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Keywords:

Desmethoxyyangonin (Standard)15345-89-8Demethoxyyangonin (Standard)5,6-Dehydrokavain (Standard)Reference StandardsMonoamine OxidaseJAKSTATNO SynthaseIKKCytochrome P450MAOJanus kinaseNitric oxide synthasesNOSIκB kinaseI kappa B kinase CYPsInflammationImmunologyRAW 264.7 cellsMice LPS/D-GalN-induced fulminant hepatitis modelInhibitorinhibitorinhibit

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