2. Immunology/Inflammation
  3. COX
  4. COX-2-IN-58

COX-2-IN-58 is a COX-2 inhibitor. COX-2-IN-58 exhibits remarkable anti-inflammatory activity in Carrageenan (HY-125474)-induced paw edema model of Balb/C mice. COX-2-IN-58 can be used for the research of inflammation.

For research use only. We do not sell to patients.

COX-2-IN-58

COX-2-IN-58 Chemical Structure

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COX-2-IN-58 Related Antibodies

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Description

COX-2-IN-58 is a COX-2 inhibitor. COX-2-IN-58 exhibits remarkable anti-inflammatory activity in Carrageenan (HY-125474)-induced paw edema model of Balb/C mice. COX-2-IN-58 can be used for the research of inflammation[1].

IC50 & Target[1]

COX-2

 

In Vivo

COX-2-IN-58 (Compound 10) (i.p., single dose) exhibits remarkable anti-inflammatory activity in Carrageenan (HY-125474)-induced paw edema model of Balb/C mice(20-22 g)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

389.38

Formula

C22H16FN3O3
SMILES

CC(C1=NN=C(O1)C2=CC=CC=C2[N+]([O-])=O)C3=CC=C(C(F)=C3)C4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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COX-2-IN-58 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

COX-2-IN-58COXCyclooxygenaseinflammationCOX-2Inhibitorinhibitorinhibit

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COX-2-IN-58
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HY-175643
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