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  3. Reference Standards Endogenous Metabolite
  4. ATP (Standard)

ATP (Standard)  (Synonyms: Adenosine 5'-triphosphate (Standard))

Cat. No.: HY-B2176R Purity: 95.70%
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Handling Instructions Technical Support

ATP (Standard) is the analytical standard of ATP. This product is intended for research and analytical applications. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. In Vitro: ATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.
ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner.
ATP promotes neutrophil chemotaxis in vitro.
In Vivo: ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo.

For research use only. We do not sell to patients.

ATP (Standard)

ATP (Standard) Chemical Structure

CAS No. : 56-65-5

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Information

ATP (Standard) is the analytical standard of ATP. This product is intended for research and analytical applications. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. In Vitro: ATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.
ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner.
ATP promotes neutrophil chemotaxis in vitro.
In Vivo: ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo.
Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

507.18

Formula

C10H16N5O13P3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(O)(O)OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](O)[C@@H]1O)(O)=O)(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 95.70%

SDS (252 KB)

COA (152 KB) HNMR (288 KB) RP-HPLC (374 KB) MS (206 KB)

Handling Instructions (2659 KB)
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ATP (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATP (Standard)56-65-5Adenosine 5'-triphosphate (Standard)Reference StandardsEndogenous MetaboliteenergystoragemetabolismimmunityinflammationNLRP3inflammasomecytokineInhibitorinhibitorinhibit

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