2. Neuronal Signaling
  3. Monoamine Oxidase
  4. (R)-Pirlindole mesylate

(R)-Pirlindole mesylate is selective and reversible a Monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.43  μM for MAO-A over MAO-B. (R)-Pirlindole mesylate has an antidepressant activity. (R)-Pirlindole mesylate significantly decreases immobility time of the forced swim test and inhibits Reserpine (HY-N0480)-induced palpebral ptosis in behavioural mice models. (R)-Pirlindole mesylate can be used for depression research.

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(R)-Pirlindole mesylate

(R)-Pirlindole mesylate Chemical Structure

CAS No. : 1821379-62-7

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(R)-Pirlindole mesylate Related Antibodies

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Description

(R)-Pirlindole mesylate is selective and reversible a Monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.43  μM for MAO-A over MAO-B. (R)-Pirlindole mesylate has an antidepressant activity. (R)-Pirlindole mesylate significantly decreases immobility time of the forced swim test and inhibits Reserpine (HY-N0480)-induced palpebral ptosis in behavioural mice models. (R)-Pirlindole mesylate can be used for depression research[1].

IC50 & Target[1]

MAO-A

0.43 μM (IC50)

Molecular Weight

322.42

Formula

C16H22N2O3S
CAS No.
SMILES

CS(=O)(O)=O.CC1=CC=C2N(CCN[C@]3([H])CCC4)C3=C4C2=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(R)-Pirlindole mesylate Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-Pirlindole1821379-62-7Monoamine OxidaseMAOInhibitorMonoamine oxidase AMAO-AAntidepressantBehavioural mice modelsDepressioninhibitorinhibit

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