2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. LY 190388

LY 190388 is a penicillamine-containing enkefa peptide analog with μ receptor agonist activity. LY 190388 showed analgesic effect in inhibiting the writhing response in mice after intracerebroventricular administration. The analgesic effect of LY 190388 is not caused by its δ receptor agonist action, but by its μ receptor agonist activity. When LY 190388 is used together with the δ receptor antagonist ICI 174864, an additive analgesic effect is produced.

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LY 190388

LY 190388 Chemical Structure

CAS No. : 105496-35-3

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Description

LY 190388 is a penicillamine-containing enkefa peptide analog with μ receptor agonist activity. LY 190388 showed analgesic effect in inhibiting the writhing response in mice after intracerebroventricular administration. The analgesic effect of LY 190388 is not caused by its δ receptor agonist action, but by its μ receptor agonist activity. When LY 190388 is used together with the δ receptor antagonist ICI 174864, an additive analgesic effect is produced[1].

Molecular Weight

615.74

Formula

C30H41N5O7S
CAS No.
Sequence

Tyr-{d-Pen}-Gly-Phe-{d-Val}
Sequence Shortening

Y-{d-Pen}-GF-{d-Val}
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LY 190388 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY 190388105496-35-3LY190388LY-190388Endogenous MetaboliteInhibitorinhibitorinhibit

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