2. Cell Cycle/DNA Damage Protein Tyrosine Kinase/RTK
  3. STK33 CDK RET
  4. CDD-2807

CDD-2807 is an inhibitor for serine/threonine kinase 33 (STK33) with IC50 of 9.2 nM. CDD-2807 exhibits no significant toxicity in mice and can cross the blood-testis barrier without accumulating in the brain. CDD-2807 induces a reversible contraceptive effect and has potential for the development of the male contraceptive.

For research use only. We do not sell to patients.

CDD-2807 Chemical Structure

CDD-2807 Chemical Structure

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CDD-2807 Related Antibodies

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Description

CDD-2807 is an inhibitor for serine/threonine kinase 33 (STK33) with IC50 of 9.2 nM. CDD-2807 exhibits no significant toxicity in mice and can cross the blood-testis barrier without accumulating in the brain. CDD-2807 induces a reversible contraceptive effect and has potential for the development of the male contraceptive[1].

IC50 & Target

STK33

9.2 nM (IC50)

CLK4

85 nM (IC50)

CLK2

101 nM (IC50)

CLK1

116 nM (IC50)

RET

363 nM (IC50)

Molecular Weight

446.54

Formula

C29H26N4O
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC2=C(NN=C2C#CC3=CC=CC=C3C4=CC=CC=C4)C=C1)N5CC6(CNCCC6)C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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CDD-2807 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDD-2807CDD2807CDD 2807STK33CDKRETSerine/threonine kinase 33Cyclin dependent kinasecontraceptiveBBB penetrateInhibitorinhibitorinhibit

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