2. Others Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Cell Cycle/DNA Damage Immunology/Inflammation
  3. Biochemical Assay Reagents PPAR Interleukin Related S100 Protein
  4. Perfluoropentanoic acid

Perfluoropentanoic acid  (Synonyms: PFPeA; Perfluorovaleric acid)

Cat. No.: HY-21193 Purity: ≥98.0%
COA
SDS
Handling Instructions Technical Support

Perfluoropentanoic acid (PFPeA), a short-chain perfluorinated compound, serves as an important indicator of perfluorinated compound pollution in ecosystems. Perfluoropentanoic acid exhibits certain toxicity to mice.

For research use only. We do not sell to patients.

Perfluoropentanoic acid Chemical Structure

Perfluoropentanoic acid Chemical Structure

CAS No. : 2706-90-3

Size Price Stock Quantity
1 g In-stock
5 g In-stock
10 g In-stock
25 g In-stock
100 g In-stock
> 100 g   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Perfluoropentanoic acid:

Perfluoropentanoic acid Related Antibodies

Top Publications Citing Use of Products

View All PPAR Isoform Specific Products:

View All Isoforms
PPARα PPARβ/δ PPARγ PPAR PPARδ

View All Interleukin Related Isoform Specific Products:

View All Isoforms
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Perfluoropentanoic acid (PFPeA), a short-chain perfluorinated compound, serves as an important indicator of perfluorinated compound pollution in ecosystems. Perfluoropentanoic acid exhibits certain toxicity to mice[1][2].

IC50 & Target[2]

PPARδ

 

PPARγ

 

IL-6

 

In Vitro

Perfluoropentanoic acid can significantly affect the structure and spatial distribution of planktonic microbial communities and may threaten water quality through microbial metabolism[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Perfluoropentanoic acid Related Antibodies
In Vivo

Perfluoropentanoic acid (1.25-5% w/v; topical administration; 28 days) can cause liver damage, skin inflammation, immune cell activation and abnormal expression of related genes in mice[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female B6C3F1 mice aged 7-8 weeks old[2]
Dosage: 1.25, 2.5, 5% w/v
Administration: Topical application on the dorsal surface of each ear (25 μL/ear), once daily for 28 consecutive days
Result: Resulted in significant absorption, as evidenced by increased serum and urine concentrations.
Significantly increased liver weight at 5% dosage, accompanied by hepatocellular hypertrophy in the centrilobular region.
Elevated glucose and decreased urea nitrogen at 5% dosage in serum.
Caused epidermal hyperplasia, hyperkeratosis, dermal mixed cell inflammation, and focal fibrosis in the skin.
Increased cellularity of B cells, CD4+ and CD8+ T cells, and NK cells, with enhanced eosinophil frequency and number in draining lymph nodes.
Upregulated lipid metabolism-related genes (e.g., Cd36, Lpl, Serpine1) and altered PPAR isoform expression (Pparδ downregulation, Pparγ upregulation) in the liver, while skin gene expression showed increased inflammatory cytokines (IL-6, TSLP) and danger signals (S100a7a, S100a8), along with upregulated skin barrier genes (Flg, Krt10).
Molecular Weight

264.05

Synonyms

PFPeA; Perfluorovaleric acid

Formula

C5HF9O2
CAS No.
Appearance

Liquid (Density: 1.713 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (757.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7872 mL 18.9358 mL 37.8716 mL
5 mM 0.7574 mL 3.7872 mL 7.5743 mL
View the Complete Stock Solution Preparation Table

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7872 mL 18.9358 mL 37.8716 mL 94.6790 mL
5 mM 0.7574 mL 3.7872 mL 7.5743 mL 18.9358 mL
10 mM 0.3787 mL 1.8936 mL 3.7872 mL 9.4679 mL
15 mM 0.2525 mL 1.2624 mL 2.5248 mL 6.3119 mL
20 mM 0.1894 mL 0.9468 mL 1.8936 mL 4.7340 mL
25 mM 0.1515 mL 0.7574 mL 1.5149 mL 3.7872 mL
30 mM 0.1262 mL 0.6312 mL 1.2624 mL 3.1560 mL
40 mM 0.0947 mL 0.4734 mL 0.9468 mL 2.3670 mL
50 mM 0.0757 mL 0.3787 mL 0.7574 mL 1.8936 mL
60 mM 0.0631 mL 0.3156 mL 0.6312 mL 1.5780 mL
80 mM 0.0473 mL 0.2367 mL 0.4734 mL 1.1835 mL
100 mM 0.0379 mL 0.1894 mL 0.3787 mL 0.9468 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Perfluoropentanoic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Perfluoropentanoic acid2706-90-3PFPeA Perfluorovaleric acidBiochemical Assay ReagentsPPARInterleukin RelatedS100 ProteinPeroxisome proliferator-activated receptorsILPFC pollutionshort-chain perfluorinated compoundInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Perfluoropentanoic acid
Cat. No.:
HY-21193
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (580 KB) Français - FR (580 KB) Deutsch - DE (580 KB) Norwegian - NO (580 KB) Español - ES (580 KB) Swedish - SV (580 KB) Italian - IT (580 KB) Portuguese - PT (580 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.