2. Membrane Transporter/Ion Channel
  3. SGLT
  4. WAY-123783

WAY-123783 is a potent, selective and orally active sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor producing activity after metabolism. WAY-123783 can increase the excretion of sugar in urine and at the same time lower the blood sugar level in db/db mice (ED50 = 9.85 mg/kg). WAY-123783 can be used for the research of metabolic disease, such as diabetes.

For research use only. We do not sell to patients.

WAY-123783

WAY-123783 Chemical Structure

CAS No. : 152595-59-0

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WAY-123783 Related Antibodies

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Description

WAY-123783 is a potent, selective and orally active sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor producing activity after metabolism. WAY-123783 can increase the excretion of sugar in urine and at the same time lower the blood sugar level in db/db mice (ED50 = 9.85 mg/kg). WAY-123783 can be used for the research of metabolic disease, such as diabetes[1][2].

IC50 & Target[1]

SGLT2

 

Molecular Weight

288.29

Formula

C12H11F3N2OS
CAS No.
SMILES

O=C1NNC(C(F)(F)F)=C1CC2=CC=C(C=C2)SC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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WAY-123783 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WAY-123783152595-59-0WAY123783WAY 123783SGLTSodium-dependent glucose cotransporterssodium/glucose cotransporter 2SGLT2db/dbblood sugarurine sugardiabetesInhibitorinhibitorinhibit

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