2. Antibody-drug Conjugate/ADC Related GPCR/G Protein
  3. Antibody-Drug Conjugates (ADCs) GLP Receptor
  4. Maridebart cafraglutide

Maridebart cafraglutide (AMG 133) is an antibody-peptide conjugate acting as a GLP-1 receptor agonist and an antagonist of the GIP receptor. Maridebart cafraglutide reduces body weight and improve metabolic markers in male obese mice and cynomolgus monkeys. Maridebart cafraglutide is promising for research of obesity.

For research use only. We do not sell to patients.

Maridebart cafraglutide Chemical Structure

Maridebart cafraglutide Chemical Structure

CAS No. : 2887445-76-1

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Maridebart cafraglutide Related Antibodies

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Description

Maridebart cafraglutide (AMG 133) is an antibody-peptide conjugate acting as a GLP-1 receptor agonist and an antagonist of the GIP receptor. Maridebart cafraglutide reduces body weight and improve metabolic markers in male obese mice and cynomolgus monkeys. Maridebart cafraglutide is promising for research of obesity[1][2].

Clinical Trial
Molecular Weight

153,514 (average)

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Maridebart cafraglutide]
Shipping

Shipping with dry ice.
Storage

-80°C, protect from light
Purity & Documentation
References
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Maridebart cafraglutide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Maridebart cafraglutide2887445-76-1AMG 133AMG133AMG-133Antibody-Drug Conjugates (ADCs)GLP ReceptorAntibody-Drug Conjugatesantibody-peptide conjugateGLP-1GIPbody weightmetabolic markersmicecynomolgus monkeysobesityInhibitorinhibitorinhibit

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