2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. QLS-81

QLS-81 is a Nav1.7 channel inhibitor (IC50: 1.5 μM). QLS-81 has significant analgesic activity and can relieve neuropathic and inflammatory pain. QLS-81 exerts frequency-dependent inhibitory effects by inhibiting the inactivated state of Nav1.7 channels. QLS-81 can be used in the study of chronic pain.

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QLS-81 Chemical Structure

QLS-81 Chemical Structure

CAS No. : 2835455-57-5

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QLS-81 Related Antibodies

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Description

QLS-81 is a Nav1.7 channel inhibitor (IC50: 1.5 μM). QLS-81 has significant analgesic activity and can relieve neuropathic and inflammatory pain. QLS-81 exerts frequency-dependent inhibitory effects by inhibiting the inactivated state of Nav1.7 channels. QLS-81 can be used in the study of chronic pain[1].

Molecular Weight

330.40

Formula

C19H23FN2O2
CAS No.
SMILES

C[C@H](NCCCC1=CC=C(OCC2=CC=CC=C2F)C=C1)C(N)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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QLS-81 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

QLS-812835455-57-5QLS81QLS 81Sodium ChannelNa channelsNa+ channelsHEK293 cellsDRGneuropathic paininflammatory painC57BL/6J miceInhibitorinhibitorinhibit

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