2. Anti-infection
  3. Parasite
  4. Antimalarial agent 51

Antimalarial agent 51 (Compound 2) is an orally active antimalarial compound. Antimalarial agent 51 blocks nutrient uptake by Plasmodium by inhibiting the plasmodium surface anion channel (PSAC). Antimalarial agent 51 significantly inhibits the growth of Plasmodium under nutrient-restricted conditions. Combination of antimalarial agent 51 with the residual transport inhibitor PRT-2 can enhance the antimalarial effect. Antimalarial agent 51 can be used in the study of malaria targeting the PSAC channel.

For research use only. We do not sell to patients.

Antimalarial agent 51 Chemical Structure

Antimalarial agent 51 Chemical Structure

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Antimalarial agent 51 Related Antibodies

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Description

Antimalarial agent 51 (Compound 2) is an orally active antimalarial compound. Antimalarial agent 51 blocks nutrient uptake by Plasmodium by inhibiting the plasmodium surface anion channel (PSAC). Antimalarial agent 51 significantly inhibits the growth of Plasmodium under nutrient-restricted conditions. Combination of antimalarial agent 51 with the residual transport inhibitor PRT-2 can enhance the antimalarial effect. Antimalarial agent 51 can be used in the study of malaria targeting the PSAC channel[1].

Molecular Weight

347.41

Formula

C20H21N5O
SMILES

O=C(N(C1)CC[C@@]21C[C@@H](NC3=NC=NC=C3)C2)C4=CC5=C(C=CC=C5)N4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antimalarial agent 51 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antimalarial agent 51Antimalarial agent51Antimalarial agent-51ParasiteHepG2 cellsNSG mice3D7ALDHCLAG3PSACInhibitorinhibitorinhibit

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